Fig. 5
From: An in vitro investigation into the impact of corneal rinsing on riboflavin/UVA corneal cross-linking
Graphical representation of fluorescence intensity profiles through the anterior-most region of the corneal stroma (0 to 300 μm) following application of a 0.1% riboflavin/1.0% HPMC solution with no BSS rinse (Group 3), a 0.25 mL rinse (Group 4), 1 mL rinse (Group 5) or 10 mL rinse (Group 6) (n = 3 per group). The 10 mL BSS rinse group showed a significantly lower intensity in the anterior-most 300 µm compared to the no rinse (P < 0.05), 0.25 mL rinse (P < 0.05) and 1 mL rinse (P < 0.05) groups. Trendlines: Moving average using 10 data points. CXL, corneal cross-linking; UVA, ultraviolet-A light; BSS, balanced salt solution; HPMC, hydroxypropyl methylcellulose; CCT, central corneal thickness