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Table 3 The risk factors with recurrence of mCNV

From: Myopic choroidal neovascularization with neovascular signal around perforating scleral vessel prone to recur after anti-VEGF therapy

Variable

Sub-group

Univariate analysis

Multivariate analysis

P value

HR

95% CI for HR

P value

HR

95% CI for HR

5%

95%

5%

95%

Subfoveal choroidal thickness

10–50 μm (47.1%)

0.0496

1.000

0.034

1.000

51–110 μm (52.9%)

 

2.526

1.002

6.371

 

0.368

0.146

0.928

Neovascular signal around PSV

Absence (60.8%)

0.038

1.000

0.026

1.000

Presence (39.2%)

 

2.705

1.057

6.922

 

2.904

1.134

7.436

Anti-VEGF

Conbercept (45.1%)

0.266

1.000

Ranibizumab (54.9%)

 

1.658

0.68

4.043

Lacquer cracks

Absence (68.6%)

0.116

1.000

Presence (31.4%)

 

2.034

0.839

4.930

Baseline CNV area

 < 0.3 mm2 (37.3%)

0.089

1.000

0.3–0.7 mm2 (33.3%)

 

3.007

1.016

8.899

 > 0.7 mm2 (29.4%)

 

1.081

0.328

3.565

Baseline BCVA

0.005–0.5 logMAR (31.4%)

0.943

1.000

0.5–1.0 logMAR (43.1%)

 

1.191

0.423

3.357

1.0–2.0 logMAR (25.5%)

 

1.062

0.323

3.485

  1. mCNV = myopic choroidal neovascularization; PSV = perorating scleral vessels; anti-VEGF = anti-vascular endothelial growth factor; CNV = choroidal neovascularization; BCVA = best-corrected visual acuity; CI = confidence interval; HR = hazard ratio
  2. Bold values indicate statistically significant
  3. P < 0.05 was considered as significant