Parameter | DED (n = 70) | NC (n = 70) | P value |
|---|
Age (years) | 25 (23–25) | 24 (23–24) | 0.761 |
Gender (M:F) | 4:31 | 8:27 | 0.342 |
OSDI score | 29.35 ± 9.91 | 4.67 ± 3.86 | < 0.001 |
NIBUT (s) | 7.84 ± 4.31 | 14.97 ± 5.74 | < 0.001 |
FBUT (s) | 3 (2.75–4) | 8 (6–10) | < 0.001 |
SIT (mm) | 7 (4–14) | 12 (5–25) | 0.023 |
FCS | 0 (0–1) | 0 (0–0) | 0.003 |
- The data are presented as mean ± standard deviation, or median (interquartile range). Age, gender and OSDI score are compared between 35 DED subjects and 35 NC. NIBUT, FBUT, SIT and FCS are compared between 70 eyes from DED subjects and 70 eyes from NC
- DED = dry eye disease; n = number of eyes; NC = normal controls; M = male; F = female; OSDI = ocular surface disease index; NIBUT = non-invasive tear break-up time; FBUT = fluorescein tear film break-up time; SIT = Schirmer’s I test; FCS = fluorescein corneal staining
