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Table 3 Logistic regression to identify factors associated with residual fluid after three loading doses of aflibercept

From: Features of optical coherence tomography angiography in age-related macular degeneration with residual fluid after three loading doses of aflibercept

Parameter

Univariable

Multivariable

 

OR (95% CI)

P value

OR (95% CI)

P value

Age

1.01 (0.96, 1.07)

0.622

  

Sex

0.70 (0.28, 1.75)

0.443

  

Spherical equivalent

1.25 (0.90, 1.72)

0.185

  

Intraocular pressure

1.02 (0.90, 1.15)

0.786

  

Axial length

1.82 (0.95, 3.49)

0.073

  

BCVA

0.71 (0.30, 1.70)

0.441

  

MNV type

1.83 (0.80, 4.18)

0.154

  

CT

0.99 (0.99, 1.00)

0.743

  

CMT

1.00 (0.99, 1.00)

0.884

  

HF

1.55 (0.99, 2.69)

0.118

  

SHRM

1.60 (0.70, 3.66)

0.270

  

PED height

0.99 (0.99, 1.00)

0.397

  

GVC

0.99 (0.97, 1.01)

0.231

  

GLD

1.00 (0.99, 1.00)

0.179

  

Branching

2.40 (0.73, 7.88)

0.149

  

Loop

2.74 (1.12, 6.71)

0.028

1.45 (0.52, 4.02)

0.480

Peripheral arcade

5.50 (2.26, 13.37)

< 0.001

4.77 (1.82, 12.49)

0.001

Hypointense halo

0.55 (0.03, 9.01)

0.673

  

MNV size

0.87 (0.71, 1.07)

0.180

  

VD

0.97 (0.94, 1.00)

0.057

  
  1. BCVA = best-corrected visual acuity; MNV = macular neovascularization; CT = choroidal thickness; CMT = central macular thickness; HF = hyperreflective foci; SHRM = subretinal hyperreflective material; PED = pigment epithelium detachment; GVC = greatest vascular caliber; GLD = greatest linear dimension; MNV = macular neovascularization; VD = vessel density
  2. Values in boldface are statistically significant (P < 0.050)