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Table 2 Characteristics of optical coherence tomography angiography at baseline and final visit in each group

From: Features of optical coherence tomography angiography in age-related macular degeneration with residual fluid after three loading doses of aflibercept

Parameter

Group 1

Group 2

 
 

Baseline

Final

P value*

Baseline

Final

P value*

P value

GVC (µm)

77.0 ± 28.7

60.7 ± 23.9

< 0.001

68.6 ± 30.3

59.0 ± 31.5

< 0.001

0.231§

GLD (µm)

2277.0 ± 963.1

2011.6 ± 997.9

< 0.001

1966.7 ± 952.0

1701.3 ± 969.2

< 0.001

0.178§

MNV size (mm2)

2.94 ± 2.51

2.32 ± 2.19

< 0.001

2.22 ± 2.26

1.65 ± 1.70

< 0.001

0.178§

VD (%)

47.1 ± 15.4

42.4 ± 14.6

< 0.001

41.3 ± 10.5

38.5 ± 10.9

< 0.001

0.052§

Branching (n, %)

50 (76.9)

19 (29.2)

< 0.001 Π

32 (88.9)

10 (27.8)

< 0.001 Π

0.141#

Loop (n, %)

34 (52.3)

27 (41.5)

0.016 Π

27 (75.0)

23 (63.9)

0.093Π

0.026 #

Peripheral arcade (n, %)

19 (29.2)

16 (24.6)

0.253Π

25 (69.4)

20 (55.6)

0.087Π

< 0.001 #

Hypointense halo (n, %)

64 (98.5)

60 (92.3)

0.066Π

35 (97.2)

29 (80.6)

0.059Π

0.669#

  1. GVC = greatest vascular caliber; GLD = greatest linear dimension; MNV = macular neovascularization; VD = vessel density
  2. Data are presented as mean ± standard deviation unless otherwise stated
  3. Values in boldface are statistically significant (P < 0.050)
  4. *Comparison for baseline vs. final
  5. Comparison for Group 1 vs. Group 2 at baseline
  6. Paired t-test; §Independent t-test; ΠGeneralized estimating equation; #Chi-squared test