Features of optical coherence tomography angiography in age-related macular degeneration with residual fluid after three loading doses of aflibercept

Table 1 Baseline demographics and OCT characteristics in each group

Parameter	Group 1 (n = 65)	Group 2 (n = 36)	P value
Age (years)	69.5 ± 7.5	70.3 ± 7.6	0.626^*
Sex (male, %)	21 (32.3)	9 (25.0)	0.441^†
Spherical equivalent (diopter)	0.15 ± 1.48	0.53 ± 1.14	0.183^*
Intraocular pressure (mmHg)	13.8 ± 3.3	13.9 ± 3.5	0.788^*
Axial length (mm)	23.6 ± 0.8	24.0 ± 0.9	0.066^*
Baseline BCVA (logMAR)	0.53 ± 0.60	0.44 ± 0.34	0.441^*
MNV type (1:2)	42:23	18:18	0.152^†
CT (µm)	264.4 ± 81.3	258.9 ± 79.6	0.746^*
CMT (µm)	390.7 ± 110.0	394.0 ± 105.7	0.885^*
PED height (µm)	194.5 ± 157.0	168.3 ± 129.4	0.397^*
Fluid type			0.478^†
SRF (n, %)	39 (60.0)	26 (72.2)
IRF (n, %)	4 (6.2)	1 (2.8)
Both (n, %)	22 (33.8)	9 (25.0)
Hyperreflective foci (n, %)	55 (84.6)	34 (94.4)	0.432^†
SHRM (n, %)	23 (35.4)	17 (47.2)	0.269^†
Prechoroidal cleft (n, %)	1 (0.5)	2 (5.6)	0.261^†

OCT = optical coherence tomography; BCVA = best-corrected visual acuity; MNV = macular neovascularization; CT = choroidal thickness; CMT = central macular thickness; PED = pigment epithelium detachment; SRF = subretinal fluid; IRF = intraretinal fluid; SHRM = subretinal hyperreflective material
Data are presented as mean ± standard deviation unless otherwise stated
^*Independent t-test; ^†Chi-squared test

ISSN: 2326-0254