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Table 2 Development of intraocular pressure (IOP), number of IOP-lowering medications and BCVA during 24 months of postoperative follow-up after trabeculectomy (TE) or PRESERFLO (PF) implantation

From: PRESERFLO MicroShunt implantation versus trabeculectomy for primary open-angle glaucoma: a two-year follow-up study

Parameter

TE

P*

PF MicroShunt

P*

P#

IOP (mmHg)

Baseline

24.09 ± 1.15

(22.50, 11.00)

n.a

21.67 ± 0.77

(21.00, 8.50)

n.a

0.160

3 months

10.91 ± 0.66

(11.00, 5.00)

 < 0.001

11.19 ± 0.78

(10.00, 4.50)

 < 0.001

0.925

6 months

11.94 ± 0.74

(11.00, 6.00)

 < 0.001

15.97 ± 0.99

(14.00, 7.50)

 < 0.001

 < 0.001

12 months

12.18 ± 0.73

(12.00, 6.00)

 < 0.001

12.75 ± 0.75

(12.00, 3.00)

 < 0.001

0.534

24 months

11.37 ± 1.13

(12.00, 7.00)

 < 0.001

15.50 ± 1.54

(14.50, 4.50)

0.028

0.183

Medication (n)

Baseline

3.25 ± 0.14

(4.00, 1.00)

n.a

3.51 ± 0.14

(4.00, 1.00)

n.a

0.360

3 months

0.20 ± 0.10

(0.00 0.00)

 < 0.001

0.12 ± 0.07

(0.00, 0.00)

 < 0.001

0.687

6 months

0.43 ± 0.14

(0.00, 0.00)

 < 0.001

0.45 ± 0.16

(0.00, 0.00)

 < 0.001

0.460

12 months

0.60 ± 0.18

(0.00, 0.00)

 < 0.001

0.64 ± 0.19

(0.00, 1.00)

 < 0.001

0.558

24 months

0.53 ± 0.14

(0.00 1.00)

 < 0.001

1.06 ± 0.43

(0.00, 1.30)

 < 0.001

0.589

BCVA (logMAR)

Baseline

0.33 ± 0.03

(0.20, 0.30)

n.a

0.31 ± 0.04

(0.20, 0.30)

n.a

0.547

3 months

0.36 ± 0.04

(0.20, 0.40)

0.535

0.26 ± 0.04

(0.20, 0.30)

0.574

0.289

6 months

0.28 ± 0.04

(0.20, 0.30)

0.172

0.28 ± 0.05

(0.20, 0.40)

0.898

0.944

12 months

0.34 ± 0.04

(0.30, 0.40)

0.923

0.33 ± 0.07

(0.20, 0.20)

0.868

0.302

24 months

0.38 ± 0.05

(0.20, 0.40)

0.223

0.40 ± 0.14

(0.20, 0.40)

0.628

0.709

  1. Bold values indicate statistically significant
  2. IOP = intraocular pressure; BCVA = best-corrected visual acuity; TE = trabeculectomy; PF = PRESERFLO
  3. * Wilcoxon-test; #Mann–Whitney U test