Fig. 1
OCT data processing. a Schematic diagram of the crystalline lens [left half: structure of the crystalline lens, and right half: optical signal discontinuity (OSD) zones] and region of interest (ROI, red) for generating densitograms for the zones. The epithelial cell layer is not shown to scale. b Three-dimensional swept-source OCT volumetric (8 × 8 × 7 mm3) dataset of a 49-year-old subject. c Refraction correction of the central B-scan. The surfaces of the anterior and posterior of the lens (solid yellow) and the nucleus (dashed yellow) were used to measure the radii of curvature. d Densitogram of the lens and identification of the OSD zones based on Oxford system nomenclature. Hyper-reflective zones are indicated by bright grey colour. Hypo-reflective zones are indicated by dark grey colour. The thickness and optical density were measured for each zone