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Fig. 4 | Eye and Vision

Fig. 4

From: Homocysteine and mitochondrial quality control in diabetic retinopathy

Fig. 4

Mitophagy flux and homocysteine. Human retinal endothelial cells were (a) stained with Mtphagy dye and scanned under PerCP Cy5.5 channel in a BD Accuri C6 plus flow cytometer. b Plot showing relative fluorescence intensity of Mtphagy dye; results are presented as mean ± SD from three different cell preparations, with each measurement made in duplicates. NG, 5 mM d-glucose; HG and HG/Hcy, 20 mM d-glucose without and with homocysteine, respectively; Hcy/GY, 20 mM d-glucose with homocysteine and GYY4137; L-Gl, 20 mM l-glucose; Rapa, 5 mM d-glucose with rapamycin. *P < 0.05 vs. NG; #P < 0.05 vs. HG

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