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Fig. 5 | Eye and Vision

Fig. 5

From: Activation of multiple Eph receptors on neuronal membranes correlates with the onset of optic neuropathy

Fig. 5

Super-resolution imaging and co-localization analysis of multiple EphA-class receptors in neuronal and glial cells within the inner plexiform layer (IPL) of 48 h optic nerve crush (ONC) retinas (injured). a Stochastic optical reconstruction microscopy (STORM) imaging of phosphorylated Eph receptors A2, A3, and A4 (pEphAs) in injured retinas. b Optical transport colocalization (OTC) analysis comparing the localization of pEphAs to neuronal cells (TUBB3) in uninjured and injured retinas. c OTC analysis comparing the localization of pEphBs to neuronal cells (TUBB3) and glial cells (GLUL) in injured retinas. N = 3 biological replicates are graphed; One biological replicate is depicted in the representative image. Mann–Whitney U tests and a P value of less than 0.05 is considered statistically significant. ***P ≤ 0.001. Scale bar at 10 μm

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Eye and Vision

ISSN: 2326-0254