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Table 1 General characteristics (demographic, behavioural and genetic) between cases and controls

From: Interaction between genetics and the adherence to the Mediterranean diet: the risk for age-related macular degeneration. Coimbra Eye Study Report 8

Parameters

Cases

(n = 161)

Controls

(n = 451)

P value

Gender, n (%)

  

0.120

 Female

101 (62.7%)

251 (55.7%)

 

 Male

60 (37.3%)

200 (44.3%)

 

Age, mean (SD)

74.8 (6.8)

71.8 (6.4)

< 0.001

Smoking, n (%)

  

0.600

 Non-smoker

136 (84.5%)

386 (86.0%)

 

 Smoker/ex-smoker

25 (15.5%)

63 (14.0%)

 

Obesity, n (%)

  

0.140

 BMI < 25 kg/m2

47 (29.4%)

106 (23.5%)

 

 BMI ≥ 25 kg/m2

113 (70.6%)

345 (76.5%)

 

Educational status, n (%)

  

0.200

 Basic education

136 (84.5%)

382 (84.7%)

 

 High school

10 (6.2%)

36 (8.0%)

 

 Higher education

3 (1.9%)

16 (3.5%)

 

 Without education

12 (7.5%)

17 (3.8%)

 

Physical exercise, n (%)

  

0.008

 No

104 (64.6%)

237 (52.5%)

 

 Yes

57 (35.4%)

214 (47.5%)

 

Genetic risk score, n (%)

  

< 0.001

 Low GRS

62 (38.5%)

244 (54.1%)

 

 High GRS

99 (61.5%)

207 (45.9%)

 

mediSCORE, n (%)

  

< 0.001

 High

15 (9.3%)

105 (23.3%)

 

 Low

146 (90.7%)

346 (76.7%)

 

mediSCORE componentsa, n (%)

   

 Vegetables

62 (38.5%)

243 (53.9%)

< 0.001

 Legumes

77 (47.8%)

249 (55.2%)

0.110

 Fruits

59 (36.6%)

250 (55.4%)

< 0.001

 Cereals

90 (55.9%)

225 (49.9%)

0.200

 Fish

90 (55.9%)

221 (49.0%)

0.130

 Dairy products

98 (60.9%)

214 (47.5%)

0.003

 Meat

87 (54.0%)

233 (51.7%)

0.600

 Alcohol

14 (8.7%)

36 (8.0%)

0.800

 Ratio of monounsaturated lipids/saturated lipids

71 (44.1%)

214 (47.5%)

0.500

  1. Bold values represent statistically significant differences between cases and controls with P < 0.05, using the Pearson's Chi-squared test (or Fisher's exact test, when appropriate) for categorical variables and the Mann–Whitney U Test for continuous variables
  2. n = number of subjects; SD = standard deviation; BMI = body mass index; GRS = genetic risk score; mediSCORE = adherence to the Mediterranean diet score
  3. aPercentage of subjects with food group consumption above (for beneficial food groups–vegetables, legumes, fruits, cereals, fish, ratio of monounsaturated lipids to saturated lipids and moderate alcohol intake) and below (for detrimental food groups–meat and dairy products) the sex-specific median for Mira population