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Fig. 3 | Eye and Vision

Fig. 3

From: Functional and structural changes in the neuroretina are accompanied by mitochondrial dysfunction in a type 2 diabetic mouse model

Fig. 3

Electroretinography (ERG) signal declined with time in db/db mice. a–d Stimulus–response plots showing the amplitude of scotopic ERG pSTR and b-wave response recorded from db/+ mice (n = 14) and db/db mice (n = 11) at different experimental timepoints. The responses within the rod operative range (i.e., ≤  − 0.3 log cd·s/m2) were fitted with sigmoidal curves, using the Naka-Ruston function to deduce the maximum b-wave response (Bmax) value. e The Bmax value of the two groups of mice over the experimental period. Data presented as mean ± SEM. Simple main effect analysis: *P < 0.05, **P < 0.01, ***P < 0.001

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Eye and Vision

ISSN: 2326-0254