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Table 4 Ocular aberration metrics between groups at different follow-up visits (median [range] or mean ± SD)

From: Optical changes and association with axial elongation in children wearing orthokeratology lenses of different back optic zone diameter

 

6-month

12-month

24-month

Ocular aberrations (µm)

6-MM group

(n = 21)

5-MM group

(n = 18)

P

6-MM group

(n = 18)

5-MM group

(n = 18)

P

6-MM group

(n = 19)

5-MM group

(n = 20)

P

RMS LOAs

0.62 ± 0.28

0.91 ± 0.44

0.026

0.57 [0.27 to 2.04]

0.88 [0.28 to 1.82]

0.064

0.77 [0.29 to 1.36]

0.87 [0.36 to 2.22]

0.095

Defocus \({(\mathrm{C}}_{2}^{0})\)

0.46 [0.19 to 1.13]

0.74 [0.07 to 1.68]

0.020

0.49 [0.17 to 2.01]

0.75 [0.18 to 1.81]

0.068

0.72 [0.11 to 1.25]

0.86 [0.31 to 2.20]

0.095

RMS HOAs

0.18 ± 0.08

0.35 ± 0.09

 < 0.001*

0.18 [0.10 to 0.48]

0.37 [0.22 to 0.57]

 < 0.001*

0.19 ± 0.05

0.39 ± 0.11

 < 0.001*

RMS SA

0.07 [0.02 to 0.22]

0.24 [0.06 to 0.35]

 < 0.001*

0.01 [− 0.02 to 0.03]

0.24 [0.08 to 0.37]

 < 0.001*

0.09 ± 0.05

0.26 ± 0.11

 < 0.001*

Primary SA (\({\mathrm{C}}_{4}^{0})\)

0.08 ± 0.08

0.23 ± 0.08

 < 0.001*

0.07 ± 0.09

0.24 ± 0.09

 < 0.001*

0.07 ± 0.08

0.25 ± 0.12

 < 0.001*

Secondary SA (\({\mathrm{C}}_{6}^{0})\)

0.01 [− 0.01 to 0.03]

 − 0.01 [− 0.03 to 0.05]

 < 0.001*

0.06 [0.02 to 0.22]

 − 0.01 [− 0.03 to 0.08]

0.068

0.01 ± 0.01

− 0.01 ± 0.02

0.004*

RMS coma

0.10 ± 0.05

0.20 ± 0.12

0.003*

0.10 [0.03 to 0.38]

0.20 [0.03 to 0.53]

0.051

0.13 ± 0.06

0.22 ± 0.12

0.006*

  1. RMS = root-mean-square; LOAs = lower-order aberrations; HOAs = higher-order aberrations; n = number of subjects; RMS HOAs: from third to sixth orders (inclusive); RMS SA: \({\mathrm{C}}_{4}^{0}\) and \({\mathrm{C}}_{6}^{0}\) combined; RMS coma: \({\mathrm{C}}_{3}^{-1}\), \({\mathrm{C}}_{3}^{1}\), \({\mathrm{C}}_{5}^{-1}\), and \({\mathrm{C}}_{5}^{1}\) combined
  2. 6-MM: using orthokeratology lenses with a back optic zone diameter of 6 mm; 5-MM: using orthokeratology lenses with a back optic zone diameter of 5 mm
  3. P: probability value of unpaired-t or Mann-Whitney U tests for differences between groups, after Bonferroni correction
  4. *Significantly different between groups