Table 5 Discrimination performance of the metrics derived from the simultaneous real-time analysis system in discriminating eyes with dry eye disease from normal controls
Parameter | AUC | Optimal cut-off | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|
OSI-MR | 0.95 | 0.96 | 95.0 | 83.8 |
VMR | 0.93 | 0.97 | 80.0 | 94.6 |
Mean OSI | 0.93 | 1.07 | 83.8 | 90.0 |
VA-BUT (s) | 0.91 | 11.09 | 80.0 | 86.5 |
Mean FVA | 0.85 | 0.076 | 83.8 | 80.0 |
OSI-BUV | 0.84 | 1.06 | 70.3 | 85.0 |
VA-BUT + OSI-BUV | 0.97 | − | 91.9 | 95.0 |
VMR + OSI-MR | 0.97 | − | 94.6 | 90.0 |
VA-BUT + OSI-MR | 0.96 | − | 83.8 | 95.0 |
VMR + OSI-BUV | 0.95 | − | 89.2 | 95.0 |