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Table 2 Clinical features and tear function parameters in the dry eye and normal control groups

From: Simultaneous real-time analysis of tear film optical quality dynamics and functional visual acuity in dry eye disease

Parameter

Dry eye group (n = 37)

Normal control group (n = 20)

P value

Gender (%, female)

86.5

65.0

0.119

Age (years)

24.6 ± 1.5

24.6 ± 0.9

0.784

SE (D)

 − 3.22 ± 1.75

 − 2.52 ± 2.19*

0.172

BCVA (logMAR)

 − 0.03 ± 0.05

 − 0.01 ± 0.02

0.073

OSDI total

33.24 ± 13.51

5.25 ± 4.29*

 < 0.001

 Ocular symptoms

35.58 ± 13.42*

8.75 ± 6.88

 < 0.001

 Vision-related function

30.89 ± 18.23

3.85 ± 5.35

 < 0.001

 Environmental triggers

35.81 ± 17.19

4.58 ± 6.88

 < 0.001

NIBUT (s)

6.19 ± 1.53*

17.52 ± 3.63*

 < 0.001

LTMH (mm)

0.15 ± 0.04*

0.23 ± 0.04*

 < 0.001

CFSS

0.38 ± 0.59

0.00 ± 0.00

0.005

  1. SE = spherical equivalent; BCVA = best-corrected visual acuity; OSDI = Ocular Surface Disease Index; NIBUT = non-invasive tear break-up time; LTMH = lower tear meniscus height; CFSS = corneal fluorescein staining score
  2. *Normal distribution, bold font indicates statistical significance