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Table 1 Demographic characteristics of all subjects

From: Peripapillary structural and microvascular alterations in early dysthyroid optic neuropathy

Parameters

Control

n = 34

NDON

n = 24

EDON

n = 20

DON

n = 19

P value

Eyes

50

42

30

31

 

Age (years)

42.8 ± 11.9

41.3 ± 11.9

41.4 ± 10.1

49.2 ± 9.1

0.111*

Sex (M:F)

14:20

10:14

9:11

11:8

0.438†

SE (diopter)

− 1.06 ± 1.49

− 0.74 ± 1.18

− 1.06 ± 1.90

− 0.17 ± 1.33

0.127*

IOP (mmHg)

12.30 ± 2.21

15.47 ± 2.49

15.78 ± 3.75

20.71 ± 4.85

< 0.001*

AL (mm)

23.01 ± 3.00

23.47 ± 0.81

23.30 ± 0.81

22.98 ± 0.67

0.666*

BCVA (logMAR)

− 0.02 ± 0.04

− 0.01 ± 0.03

0.03 ± 0.14

0.51 ± 0.53

< 0.001*

Exophthalmos (mm)

15.17 ± 0.75

17.38 ± 2.50

17.70 ± 3.15

21.17 ± 2.89

< 0.001*

Duration (years)

NA

2.1 ± 3.3

6.5 ± 10.3

3.2 ± 4.9

0.122*

VF-MD (dB)

–

− 0.27 ± 1.50

− 4.36 ± 1.83

− 17.80 ± 6.34

< 0.001*

VF-PSD (dB)

–

2.20 ± 1.04

3.84 ± 2.17

8.36 ± 1.81

< 0.001*

CAS (Score)

–

1.44 ± 1.40

1.70 ± 1.94

3.43 ± 1.72

0.020*

  1. Data are presented as mean ± standard deviation. Control = control eyes; TAO = thyroid-associated ophthalmopathy; DON = dysthyroid optic neuropathy; NDON = non-DON; EDON = equivocal DON; M = male; F = female; SE = spherical equivalent; IOP = intraocular pressure; AL = axial length; BCVA = best-corrected visual acuity; VF-MD = visual field mean deviation; VF-PSD = visual field pattern standard deviation; CAS = clinical activity scoring; – = not performed; NA = not applicable. Overall statistical significance for each variable was determined by One-way ANOVA. P values in bold indicate statistical significance. *One-way ANOVA. †χ2 test