From: Peripapillary structural and microvascular alterations in early dysthyroid optic neuropathy
Parameters | Control n = 34 | NDON n = 24 | EDON n = 20 | DON n = 19 | P value |
---|---|---|---|---|---|
Eyes | 50 | 42 | 30 | 31 | Â |
Age (years) | 42.8 ± 11.9 | 41.3 ± 11.9 | 41.4 ± 10.1 | 49.2 ± 9.1 | 0.111* |
Sex (M:F) | 14:20 | 10:14 | 9:11 | 11:8 | 0.438†|
SE (diopter) | − 1.06 ± 1.49 | − 0.74 ± 1.18 | − 1.06 ± 1.90 | − 0.17 ± 1.33 | 0.127* |
IOP (mmHg) | 12.30 ± 2.21 | 15.47 ± 2.49 | 15.78 ± 3.75 | 20.71 ± 4.85 | < 0.001* |
AL (mm) | 23.01 ± 3.00 | 23.47 ± 0.81 | 23.30 ± 0.81 | 22.98 ± 0.67 | 0.666* |
BCVA (logMAR) | − 0.02 ± 0.04 | − 0.01 ± 0.03 | 0.03 ± 0.14 | 0.51 ± 0.53 | < 0.001* |
Exophthalmos (mm) | 15.17 ± 0.75 | 17.38 ± 2.50 | 17.70 ± 3.15 | 21.17 ± 2.89 | < 0.001* |
Duration (years) | NA | 2.1 ± 3.3 | 6.5 ± 10.3 | 3.2 ± 4.9 | 0.122* |
VF-MD (dB) | – | − 0.27 ± 1.50 | − 4.36 ± 1.83 | − 17.80 ± 6.34 | < 0.001* |
VF-PSD (dB) | – | 2.20 ± 1.04 | 3.84 ± 2.17 | 8.36 ± 1.81 | < 0.001* |
CAS (Score) | – | 1.44 ± 1.40 | 1.70 ± 1.94 | 3.43 ± 1.72 | 0.020* |