Fig. 1
From: Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice
The complement system is activated in MMS-treated mouse retinas. a C3 expression in the retinas of MMS-treated mice was assessed by immunofluorescence staining before and 1, 3, and 7 days after MMS injection. b Semi-quantification of C3 immunoreactivity using ImageJ before and 1, 3, and 7 days after MMS injection. c C3 mRNA levels in MMS-treated mouse retinal tissue were evaluated by real-time qPCR and are expressed as the fold change compared with that in the control group after normalization to β-actin level (n = 6, ***P < 0.001 compared with control). MMS, methyl methane sulfonate; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; OS, outer segment