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Table 5 The receiver operating characteristic (ROC) curve analysis values

From: Comparisons of corneal biomechanical and tomographic parameters among thin normal cornea, forme fruste keratoconus, and mild keratoconus

Parameters   FFKC vs. TNC   MKC vs. TNC
AUC Sensitivity (%) Specificity (%) Youden index Cutoff AUC Sensitivity (%) Specificity (%) Youden index Cutoff
Kmax 0.511 58.00 52.00 0.100  > 45.0 0.840 66.00 90.00 0.560  > 47.0
ISV 0.571 54.00 62.00 0.160  > 19.00 0.980 96.00 96.00 0.920  > 27.00
IVA 0.680 66.00 64.00 0.300  > 0.13 0.976 92.00 92.00 0.840  > 0.21
KI 0.642 64.00 60.00 0.240  > 1.03 0.953 92.00 86.00 0.780  > 1.05
CKI 0.556 34.00 82.00 0.160  ≤ 1.00 0.742 64.00 92.00 0.560  > 1.01
IHA 0.722 78.00 66.00 0.440  > 3.0 0.910 80.00 100.00 0.800  > 12.3
IHD 0.849 84.00 72.00 0.560  > 0.008 0.991 96.00 98.00 0.940  > 0.018
A1T 0.594 74.00 48.00 0.220  ≤ 7.225 0.673 84.00 48.00 0.320  ≤ 7.226
A1V 0.719 58.00 80.00 0.380  > 0.160 0.700 58.00 82.00 0.400  > 0.161
A1DA 0.750 84.00 60.00 0.440  > 0.091 0.880 70.00 92.00 0.620  > 0.098
A1L 0.713 68.00 70.00 0.380  > 2.242 0.795 76.00 78.00 0.540  > 2.253
A2T 0.634 64.00 64.00 0.280  > 21.966 0.660 76.00 56.00 0.320  > 21.918
A2DA 0.766 74.00 72.00 0.760  > 0.101 0.762 62.00 82.00 0.440  > 0.104
HCDA 0.604 56.00 68.00 0.240  > 0.982 0.780 80.00 68.00 0.480  > 0.982
HCR 0.570 42.00 78.00 0.200  > 6.860 0.598 24.00 96.00 0.200  ≤ 5.745
DA 0.648 54.00 78.00 0.320  > 1.144 0.691 44.00 88.00 0.320  > 1.163
ARTh 0.616 62.00 64.00 0.260  > 384.769 0.686 38.00 96.00 0.340  ≤ 280.029
CBI 0.710 60.00 88.00 0.480  ≤ 0.766 0.624 46.00 88.00 0.340  > 0.968
  1. TNC thin normal cornea; FFKC forme fruste keratoconus; MKC mild keratoconus; AUC area under the curve; Kmax maximum keratometry from the anterior corneal surface; ISV index of surface variance; IVA index of vertical asymmetry; KI keratoconus index; CKI central keratoconus index; IHA index of height asymmetry; IHD index of height decentration; A1T time from starting until the first applanation; A1V velocity of the corneal apex during the first applanation; A1DA corneal deflection amplitude during the first applanation; A1L length at the first applanation; A2T time from starting until the second applanation; A2DA corneal deflection amplitude during the second applanation; HCDA corneal deflection amplitude at the moment of the highest corneal concavity; HCR central concave curvature at highest concavity; DA maximum deformation amplitude; ARTh ambrósio relational thickness to the horizontal profile; CBI corneal biomechanical index