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Table 5 The receiver operating characteristic (ROC) curve analysis values

From: Comparisons of corneal biomechanical and tomographic parameters among thin normal cornea, forme fruste keratoconus, and mild keratoconus

Parameters

 

FFKC vs. TNC

 

MKC vs. TNC

AUC

Sensitivity (%)

Specificity (%)

Youden index

Cutoff

AUC

Sensitivity (%)

Specificity (%)

Youden index

Cutoff

Kmax

0.511

58.00

52.00

0.100

 > 45.0

0.840

66.00

90.00

0.560

 > 47.0

ISV

0.571

54.00

62.00

0.160

 > 19.00

0.980

96.00

96.00

0.920

 > 27.00

IVA

0.680

66.00

64.00

0.300

 > 0.13

0.976

92.00

92.00

0.840

 > 0.21

KI

0.642

64.00

60.00

0.240

 > 1.03

0.953

92.00

86.00

0.780

 > 1.05

CKI

0.556

34.00

82.00

0.160

 ≤ 1.00

0.742

64.00

92.00

0.560

 > 1.01

IHA

0.722

78.00

66.00

0.440

 > 3.0

0.910

80.00

100.00

0.800

 > 12.3

IHD

0.849

84.00

72.00

0.560

 > 0.008

0.991

96.00

98.00

0.940

 > 0.018

A1T

0.594

74.00

48.00

0.220

 ≤ 7.225

0.673

84.00

48.00

0.320

 ≤ 7.226

A1V

0.719

58.00

80.00

0.380

 > 0.160

0.700

58.00

82.00

0.400

 > 0.161

A1DA

0.750

84.00

60.00

0.440

 > 0.091

0.880

70.00

92.00

0.620

 > 0.098

A1L

0.713

68.00

70.00

0.380

 > 2.242

0.795

76.00

78.00

0.540

 > 2.253

A2T

0.634

64.00

64.00

0.280

 > 21.966

0.660

76.00

56.00

0.320

 > 21.918

A2DA

0.766

74.00

72.00

0.760

 > 0.101

0.762

62.00

82.00

0.440

 > 0.104

HCDA

0.604

56.00

68.00

0.240

 > 0.982

0.780

80.00

68.00

0.480

 > 0.982

HCR

0.570

42.00

78.00

0.200

 > 6.860

0.598

24.00

96.00

0.200

 ≤ 5.745

DA

0.648

54.00

78.00

0.320

 > 1.144

0.691

44.00

88.00

0.320

 > 1.163

ARTh

0.616

62.00

64.00

0.260

 > 384.769

0.686

38.00

96.00

0.340

 ≤ 280.029

CBI

0.710

60.00

88.00

0.480

 ≤ 0.766

0.624

46.00

88.00

0.340

 > 0.968

  1. TNC thin normal cornea; FFKC forme fruste keratoconus; MKC mild keratoconus; AUC area under the curve; Kmax maximum keratometry from the anterior corneal surface; ISV index of surface variance; IVA index of vertical asymmetry; KI keratoconus index; CKI central keratoconus index; IHA index of height asymmetry; IHD index of height decentration; A1T time from starting until the first applanation; A1V velocity of the corneal apex during the first applanation; A1DA corneal deflection amplitude during the first applanation; A1L length at the first applanation; A2T time from starting until the second applanation; A2DA corneal deflection amplitude during the second applanation; HCDA corneal deflection amplitude at the moment of the highest corneal concavity; HCR central concave curvature at highest concavity; DA maximum deformation amplitude; ARTh ambrósio relational thickness to the horizontal profile; CBI corneal biomechanical index