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Table 4 Results of simple and multiple regression models based on best corrected visual acuity outcome

From: Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy

Parameters Simple regression model Multiple regression model
Coefficient Standard error 95% CI P value Coefficient Standard error 95% CI P value
Age 0.003 0.001 0.001 to 0.005  < 0.001 0.002 0.001 0.001 to 0.004 0.009
DM duration 0.004 0.002 0.001 to 0.007 0.011
ETDRS level 0.002 0.001  − 0.0003 to 0.004 0.087
Eye 0.007 0.017  − 0.027 to 0.041 0.686
VD SRCP  − 3.906 1.993  − 7.813 to 0.001 0.050
VD DRCP  − 7.258 2.344  − 11.852 to − 2.663 0.002  − 6.194 2.605  − 11.298 to − 1.089 0.017
FAZ area 0.448 0.195 0.065 to 0.830 0.022
RNFL thickness  − 0.005 0.003  − 0.012 to 0.001 0.120
GCL-IPL thickness  − 0.007 0.002  − 0.010 to − 0.004  < 0.001  − 0.004 0.002  − 0.007 to − 0.001 0.044
INL thickness  − 0.0005 0.003  − 0.006 to 0.005 0.856
OPL thickness  − 0.001 0.005  − 0.010 to 0.009 0.912
Total thickness  − 0.002 0.001  − 0.004 to 0.0002 0.079
Constant NA NA NA NA 0.575 0.196 0.191 to 0.959 0.003
  1. CI confidence interval; DM diabetes mellitus; ETDRS Early Treatment Diabetic Retinopathy Study; VD vessel density; SRCP superficial retinal capillary plexus; DRCP deep retinal capillary plexus; FAZ foveal avascular zone; RNFL retinal nerve fiber layer; GCL-IPL ganglion cell layer plus inner plexiform layer; INL inner nuclear layer; OPL outer plexiform layer; NA not applicable
  2. Bold font indicates significance of P < 0.05