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Table 4 Results of simple and multiple regression models based on best corrected visual acuity outcome

From: Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy

Parameters

Simple regression model

Multiple regression model

Coefficient

Standard error

95% CI

P value

Coefficient

Standard error

95% CI

P value

Age

0.003

0.001

0.001 to 0.005

 < 0.001

0.002

0.001

0.001 to 0.004

0.009

DM duration

0.004

0.002

0.001 to 0.007

0.011

–

–

–

–

ETDRS level

0.002

0.001

 − 0.0003 to 0.004

0.087

–

–

–

–

Eye

0.007

0.017

 − 0.027 to 0.041

0.686

–

–

–

–

VD SRCP

 − 3.906

1.993

 − 7.813 to 0.001

0.050

–

–

–

–

VD DRCP

 − 7.258

2.344

 − 11.852 to − 2.663

0.002

 − 6.194

2.605

 − 11.298 to − 1.089

0.017

FAZ area

0.448

0.195

0.065 to 0.830

0.022

–

–

–

–

RNFL thickness

 − 0.005

0.003

 − 0.012 to 0.001

0.120

–

–

–

–

GCL-IPL thickness

 − 0.007

0.002

 − 0.010 to − 0.004

 < 0.001

 − 0.004

0.002

 − 0.007 to − 0.001

0.044

INL thickness

 − 0.0005

0.003

 − 0.006 to 0.005

0.856

–

–

–

–

OPL thickness

 − 0.001

0.005

 − 0.010 to 0.009

0.912

–

–

–

–

Total thickness

 − 0.002

0.001

 − 0.004 to 0.0002

0.079

–

–

–

–

Constant

NA

NA

NA

NA

0.575

0.196

0.191 to 0.959

0.003

  1. CI confidence interval; DM diabetes mellitus; ETDRS Early Treatment Diabetic Retinopathy Study; VD vessel density; SRCP superficial retinal capillary plexus; DRCP deep retinal capillary plexus; FAZ foveal avascular zone; RNFL retinal nerve fiber layer; GCL-IPL ganglion cell layer plus inner plexiform layer; INL inner nuclear layer; OPL outer plexiform layer; NA not applicable
  2. Bold font indicates significance of P < 0.05