Skip to main content

Table 3 Comparison of retinal microvascular parameters and retinal sublayer or total thickness in control and diabetic groups after adjusting for age, duration of DM

From: Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy

  Control (G0) DR With normal BCVA (G1) DR with decreased BCVA (G2) P All groups P G0 vs. G1 P G0 vs. G2 P G1 vs. G2
Microvascular parameters
 VD SRCP 0.056 ± 0.004 0.054 ± 0.005 0.052 ± 0.006 0.004 0.038 0.002 0.128
 VD DRCP 0.072 ± 0.005 0.069 ± 0.006 0.062 ± 0.007  < 0.001 0.007  < 0.001  < 0.001
 FAZ area (mm2) 0.325 ± 0.132 0.342 ± 0.117 0.401 ± 0.097 0.019 0.466 0.008 0.196
Retinal layer thickness
 RNFL thickness (μm) 28.46 ± 2.88 30.04 ± 3.14 29.04 ± 3.64 0.214 0.082 0.272 0.849
 GCL-IPL thickness (μm) 72.40 ± 5.59 73.62 ± 4.82 70.24 ± 6.21 0.112 0.653 0.182 0.033
 INL thickness (μm) 17.52 ± 3.66 17.10 ± 3.41 17.10 ± 3.82 0.852 0.706 0.572 0.943
 OPL thickness (μm) 10.15 ± 1.49 10.89 ± 2.51 10.60 ± 2.36 0.240 0.108 0.217 0.666
 Total retinal thickness (μm) 239.46 ± 21.01 240.69 ± 16.13 236.31 ± 19.14 0.663 0.866 0.538 0.680
  1. DM  diabetes mellitus; BCVA best-corrected visual acuity; SRCP superficial retinal capillary plexus; DRCP deep retinal capillary plexus; VD vessel density; FAZ foveal avascular zone; RNFL retinal nerve fiber layer; GCL-IPL ganglion cell layer plus inner plexiform layer; INL inner nuclear layer; OPL outer plexiform layer
  2. Bold font indicates significance of P < 0.05