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Table 1 Control and diabetic retinopathy population and ocular characteristics

From: Visual acuity is correlated with ischemia and neurodegeneration in patients with early stages of diabetic retinopathy

 

Control

DR

DR with normal BCVA (G1)

DR with decreased BCVA (G2)

P value

All groups

Control vs. DR

G1 vs. G2

Population characteristics (n = 89)

 No. of participants, n

33

89

53

36

NA

NA

NA

 Age (years)

56.94 ± 7.32

54.66 ± 10.95

50.72 ± 9.43

60.47 ± 10.55

 < 0.001a

0.960a

 < 0.001a

 Sex (M/F)

12/21

54/35

36/17

18/18

0.014b

0.017b

0.089b

 BMI (kg/m2)

24.57 ± 2.49

25.40 ± 3.67

25.56 ± 3.35

25.16 ± 4.15

0.433a

0.452a

0.598a

 MAP (mmHg)

92.42 ± 10.61

96.41 ± 22.61

96.78 ± 24.11

95.82 ± 20.29

0.079c

0.372c

1.000c

 DM duration (years)

NA

9.06 ± 6.34

7.62 ± 5.27

11.19 ± 7.21

NA

NA

0.021c

 BG (mmol/L)

NA

7.78 ± 2.64

7.42 ± 2.46

8.35 ± 2.83

NA

NA

0.067a

Ocular characteristics (n = 132)

 No. of eyes, n

33

132

88

44

NA

NA

NA

 BCVA (logMAR)

 − 0.05 ± 0.05

0.01 ± 0.12

 − 0.05 ± 0.06

0.12 ± 0.14

 < 0.001c

0.008c

 < 0.001c

 SE (D)

0.16 ± 1.16

 − 0.10 ± 1.39

 − 0.13 ± 1.42

0.21 ± 1.27

0.009c

0.071c

0.038c

 IOP (mmHg)

12.53 ± 2.42

14.41 ± 3.48

14.20 ± 3.53

14.83 ± 3.37

0.012a

0.005a

0.306a

DR severity

  ETDRS 20 (n = 56)

NA

56

39

17

NA

NA

0.534b

  ETDRS 35 (n = 52)

NA

52

33

19

NA

NA

0.529b

  ETDRS 43–53 (n = 24)

NA

24

16

8

NA

NA

1.000b

  1. BCVA best-corrected visual acuity; NA not applicable; M/F male/female; BMI body mass index; MAP mean arterial pressure; DM diabetes mellitus; BG blood glucose; logMAR logarithm of the minimum angle of resolution; IOP intraocular pressure; DR diabetic retinopathy; ETDRS Early Treatment Diabetic Retinopathy
  2. at-test or ANOVA
  3. bχ2 test
  4. cKruskal-Wallis test