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Table 3 Tomographic biomechanical index (TBI) clinical studies

From: Biomechanical diagnostics of the cornea

Author / Reference

NE

(n)

Clin Ectasia

(n)

Cut-off

Sensitivity

(%)

Specificity

(%)

AUC

VAE-NT

Cut-off

Sensitivity

(%)

Specificity

(%)

AUC

Observation

Steinberg J et al. [71]

105

96

–

98.00

100

0.998

32

0.11

72.00

71.00

0.825

VAE NTT: 18 eyes

Sensitivity: 67% / Specificity: 65% / AUC: 0.732

Kataria P et al. [62]

100

100

> 0.63

99.00

100

0.995

100

> 0.09

82.00

78.00

0.793

–

Ferreira-Mendes J et al. [16]

312

118

0.335

94.40

94.90

0.988

57

0.295

89.50

91.00

0.96

–

Chan TCY et al. [72]

37

23

–

–

–

–

–

0.16

84.40

82.40

0.925

–

Sedaghat MR et al. [61]

137

145

> 0.49

100

100

1.000

–

–

–

–

–

–

Koc M et al. [73]

35

–

–

–

–

–

21

0.29

67.00

86.00

0.790

–

Koh S et al. [74]

70

–

–

–

–

–

23

> 0.259

52.17

88.57

0.751

–

  1. NE= normal eyes, VAE-NT= very asymmetric eyes with normal topography, NTT= eyes with normal topography and tomography, AUC= area under the receiver operating characteristics curve