Table 5 Comparison of suggested cutoff values and their sensitivity and specificity levels for the diagnosis of keratoconus (KC) and KC suspect (KCS) in Down syndrome (DS) patients of the present study compared to non-DS young patients in other studies
From: Tomography-based definition of keratoconus for Down syndrome patients
DS patients | Non-DS patients | ||||||
|---|---|---|---|---|---|---|---|
Cutoff | Sensitivity (%) | Specificity (%) | Cutoff | Sensitivity (%) | Specificity (%) | ||
KC | Anterior HOA | > 0.643 | 86.96 | 82.24 | > 0.801 [20] | 100.0 | 100.0 |
Posterior vertical coma | > 0.0702 | 91.30 | 76.97 | > 0.055 [20] | 100.0 | 100.0 | |
Anterior vertical coma | > 0.4124 | 73.91 | 93.42 | > 0.200 [21] | 94.1 | 96.7 | |
Total HOA | > 0.608 | 95.65 | 67.76 | > 0.908 [22] | 86.5 | 81.1 | |
KCS | Minimum corneal thickness | ≤ 480.0 | 66.67 | 90.91 | < 512.0 [23] | 64.0 | 58.0 |
Corneal volume | ≤ 55.3 | 66.67 | 75.32 | < 23.95 [24] | 79.0 | 79.3 | |
BAD-D | > 2.23 | 64.58 | 76.32 | > 1.6 [25] | 83.8 | 86.0 | |