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Table 1 Summary characteristics of eyes in the Down syndrome (DS) keratoconus (DS-KC), DS KC suspect (DS-KCS), DS non-ectatic comparison (DS-C), and non-DS normal control (NC) groups

From: Tomography-based definition of keratoconus for Down syndrome patients

Index

DS-KC

(n = 25)

DS-KCS

(n = 46)

DS-C

(n = 154)

NC

(n = 200)

P value*

UDVA (logMAR)

0.73 ± 0.57

0.58 ± 0.49

0.55 ± 0.44

0.91 ± 0.64

0.358

CDVA (logMAR)

0.29 ± 0.14

0.24 ± 0.13

0.23 ± 0.13

0.02 ± 0.08

0.279

Spherical error (D)

−1.51 ± 4.91

−0.40 ± 4.31

−0.21 ± 3.13

− 3.31 ± 3.38

0.428

Cylindrical error (D)

−2.54 ± 2.40

− 1.92 ± 1.21

−1.50 ± 1.06

−1.88 ± 1.53

0.009

Kmax (D)

50.26 ± 5.88

47.47 ± 1.65

47.09 ± 1.70

44.93 ± 1.55

< 0.001

BAD-D

2.98 ± 1.44

2.26 ± 0.66

1.72 ± 1.02

1.20 ± 0.53

< 0.001

  1. UDVA = uncorrected distance visual acuity; CDVA = corrected distance visual acuity; Kmax = maximum keratometry at 8-mm zone; BAD-D = Belin Ambrosio display-total deviation
  2. *One-way ANOVA between the three DS groups