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Table 1 Clinical Phenotypic features of south Indian STGD1 patients

From: Genetic characterization of Stargardt clinical phenotype in South Indian patients using sanger and targeted sequencing

IDAge/SexAge of onsetBCVA in BEFundusAuto FluorescenceSD-OCTERG
1716/M920/80Foveal atrophy few flecks in maculaHypo AF and hyper AF flecks observed in nasal to optic diskIS/OS lossNormal
188/M920/80Macular atrophyCentral hypo –AF, few hyper-AF flecks surroundingIS/OS lossCone dysfunction
1917/F6< 20/200Mild temporal pallor; flecks in macula and posterior pole;
RPE and choroidal atrophy, extensive loss of choriocapillaries throughout fundus
Central hypo-AF, hyper and hypo AF flecks all over fundusIS/OS lossCone-rod dysfunction
2012/M1020/80Macular atrophy with choriocapillary atrophy, few yellow flecks in maculaCentral hypo-AF, hyper-AF Flecks, surrounding atrophy, hyper and hypo-AF flecks all over the fundusIS/OS lossCone-rod dysfunction
2114/M1420/50Foveal atrophyCentral hypo-AF surrounded by hyper-AF flecksIS/OS lossCone dysfunction
227/M620/80Homo Macular atrophy, Bulls eye maculaCentral hypo-AF, surrounding ill-defined hyper-AF ring hyper-AF flecks around post pole, extending nasally anterior to vascular arcadesIS/OS lossCone-rod dysfunction
2410/F720/80Macular atrophy and flecksCentral hypo-AF surrounded by hyper-AF FlecksIS/OS lossNormal
2530/F720/120Macular atrophy, extensive loss of choriocapillaries and RPE atrophyHypo-AFIS/OS lossCone-rod dysfunction
2610/M920/200Macular atrophy and flecksHypo-AF surrounded by hyper and hypo-AF flecksIS/OS lossCone-rod dysfunction
2716/F1420/80Macular atrophyCentral area of hypo-AF with surrounding ring of hyper-AFIS/OS lossNormal
2816/M1520/50Foveal atrophy with yellow flecks in post pole, extending anterior to vascular arcadesCentral hypo-AF; few flecks anterior to vascular arcadeIS/OS lossNormal
  1. BCVA = best corrected visual acuity; BE = both eyes; AF = autofluorescence; SD-OCT = spectral domain optical coherence tomography; ERG = electroretinography; IS/OS = inner segment / outer segment layer