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Fig. 2 | Eye and Vision

Fig. 2

From: Utility of high-resolution anterior segment optical coherence tomography in the diagnosis and management of sub-clinical ocular surface squamous neoplasia

Fig. 2

HR-OCT of sub-clinical OSSN. a Slit lamp image of the left eye of a flat/opalescent ocular surface squamous neoplasia (arrow) emanating from the head of a subtle pterygium (marked by an x). Note opalescent tissue on the cornea from 7 to 9 o’clock. b High resolution optical coherence tomography (HR-OCT) revealed thickened, hyperreflective, epithelium (marked by an *) with an abrupt transition (arrow). Directly below is a subepithelial “stringy” hyperreflectivity consistent with the pterygium (marked by an o). c After 4 cycles of 5-flourouracil (5-FU), the flat/opalescent lesion at the head of the pterygium was no longer clinically visible. d HR-OCT reveals improvement but persistent sub-clinical disease (marked by an *) with residual hyperreflective thickened epithelium. e After an additional 2 cycles of 5-FU, the lesion remains clinically resolved. f Now the HR OCT confirms normalized, thin epithelium (arrow). Sub-epithelial scarring consistent with the pterygium remains as expected

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Eye and Vision

ISSN: 2326-0254