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Table 4 Changes in parameters from baseline after accelerated crosslinking with 18 mW/cm2 (Group 1) and 9 mW/cm2 (Group 2) in mild to moderate and advanced keratoconus at 12 months

From: Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus

 

Mild to Moderate Keratoconus

 

Advanced Keratoconus

 
 

Group 1 (n = 23) (Mean ± SD)

Group 2 (n = 17) (Mean ± SD)

P

Group 1 (n = 14) (Mean ± SD)

Group 2 (n = 12) (Mean ± SD)

P

UCVA (LogMAR)

−0.12 ± 0.18

− 0.07 ± 0.17

0.354

−0.14 ± 0.26

−0.11 ± 0.25

0.803

BCVA (LogMAR)

−0.07 ± 0.11

−0.10 ± 0.13

0.515

−0.13 ± 0.14

−0.19 ± 0.16

0.37

K1 (D)

−0.01 ± 0.54

−0.22 ± 2.43

0.688

0.20 ± 0.95

− 1.08 ± 1.16

0.005

K2 (D)

0.05 ± 0.61

− 0.82 ± 1.13

0.003

0.14 ± 1.03

− 1.06 ± 1.37

0.019

AvgK (D)

0.01 ± 0.53

− 0.82 ± 1.10

0.003

0.16 ± 0.90

− 1.06 ± 1.21

0.007

Cycl (D)

0.06 ± 0.41

− 0.01 ± 0.60

0.619

− 0.06 ± 0.77

0.02 ± 0.67

0.757

AKf (D)

− 0.69 ± 1.36

−1.54 ± 1.47

0.067

− 0.94 ± 1.95

−2.27 ± 1.68

0.078

AKb (D)

3.89 ± 5.69

4.97 ± 4.80

0.531

3.40 ± 6.82

4.91 ± 3.82

0.504

Slf (D)

−0.28 ± 0.66

−0.64 ± 0.90

0.153

− 0.44 ± 1.27

−1.21 ± 0.56

0.065

Slb (D)

0.13 ± 0.25

0.12 ± 0.22

0.827

− 0.02 ± 0.25

−0.02 ± 0.36

0.94

Thin (μm)

−21.08 ± 23.60

−42.00 ± 28.61

0.016

− 18.21 ± 15.65

−38.58 ± 21.21

0.01

Vol (mm3)

−0.93 ± 1.46

−1.13 ± 2.83

0.777

− 1.18 ± 1.9

− 1.48 ± 2.73

0.747

CCT (μm)

− 11.82 ± 18.94

−21.05 ± 20.15

0.146

− 9.92 ± 18.77

−24.58 ± 23.86

0.092

  1. UCVA = uncorrected visual acuity; BCVA = best-corrected visual acuity; K1 = flat keratometry; K2 = steep keratometry; AvgK = average keratometry; Cyl = topographic cylindrical value; AKf = apical keratoscopy front (Kmax); AKb = apical keratoscopy back; SIf = symmetry index front; SIb = symmetry index back; Thin = thinnest point of cornea; Vol = corneal volume; CCT = central corneal thickness; D = diopters
  2. P: Paired t test; Values in bold are significant (P < 0.05)