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Table 4 Changes in parameters from baseline after accelerated crosslinking with 18 mW/cm2 (Group 1) and 9 mW/cm2 (Group 2) in mild to moderate and advanced keratoconus at 12 months

From: Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus

  Mild to Moderate Keratoconus   Advanced Keratoconus  
  Group 1 (n = 23) (Mean ± SD) Group 2 (n = 17) (Mean ± SD) P Group 1 (n = 14) (Mean ± SD) Group 2 (n = 12) (Mean ± SD) P
UCVA (LogMAR) −0.12 ± 0.18 − 0.07 ± 0.17 0.354 −0.14 ± 0.26 −0.11 ± 0.25 0.803
BCVA (LogMAR) −0.07 ± 0.11 −0.10 ± 0.13 0.515 −0.13 ± 0.14 −0.19 ± 0.16 0.37
K1 (D) −0.01 ± 0.54 −0.22 ± 2.43 0.688 0.20 ± 0.95 − 1.08 ± 1.16 0.005
K2 (D) 0.05 ± 0.61 − 0.82 ± 1.13 0.003 0.14 ± 1.03 − 1.06 ± 1.37 0.019
AvgK (D) 0.01 ± 0.53 − 0.82 ± 1.10 0.003 0.16 ± 0.90 − 1.06 ± 1.21 0.007
Cycl (D) 0.06 ± 0.41 − 0.01 ± 0.60 0.619 − 0.06 ± 0.77 0.02 ± 0.67 0.757
AKf (D) − 0.69 ± 1.36 −1.54 ± 1.47 0.067 − 0.94 ± 1.95 −2.27 ± 1.68 0.078
AKb (D) 3.89 ± 5.69 4.97 ± 4.80 0.531 3.40 ± 6.82 4.91 ± 3.82 0.504
Slf (D) −0.28 ± 0.66 −0.64 ± 0.90 0.153 − 0.44 ± 1.27 −1.21 ± 0.56 0.065
Slb (D) 0.13 ± 0.25 0.12 ± 0.22 0.827 − 0.02 ± 0.25 −0.02 ± 0.36 0.94
Thin (μm) −21.08 ± 23.60 −42.00 ± 28.61 0.016 − 18.21 ± 15.65 −38.58 ± 21.21 0.01
Vol (mm3) −0.93 ± 1.46 −1.13 ± 2.83 0.777 − 1.18 ± 1.9 − 1.48 ± 2.73 0.747
CCT (μm) − 11.82 ± 18.94 −21.05 ± 20.15 0.146 − 9.92 ± 18.77 −24.58 ± 23.86 0.092
  1. UCVA = uncorrected visual acuity; BCVA = best-corrected visual acuity; K1 = flat keratometry; K2 = steep keratometry; AvgK = average keratometry; Cyl = topographic cylindrical value; AKf = apical keratoscopy front (Kmax); AKb = apical keratoscopy back; SIf = symmetry index front; SIb = symmetry index back; Thin = thinnest point of cornea; Vol = corneal volume; CCT = central corneal thickness; D = diopters
  2. P: Paired t test; Values in bold are significant (P < 0.05)