Microvascular blood flow velocities measured with a retinal function imager: inter-eye correlations in healthy controls and an exploration in multiple sclerosis

Table 2 Comparisons of blood flow velocities

	HC - OD	HC - OS	All MS eyes	MSNON eyes	MSON eyes	P value
	(20, eyes)	(20, eyes)	(38, eyes)	(25, eyes)	(13, eyes)	(OD vs. OS in HCs)	(All MS vs. HCs)	(MSNON vs. HCs)	(MSON vs. HCs)	(MSON vs. MSNON)
Arterioles, mm/s; mean (SD)	3.95 (0.59)	4.08 (0.60)	3.51 (0.81)	3.48 (0.88)	3.59 (0.69)	0.1^a	0.01 ^b	0.009 ^b	0.046 ^b	0.42^b
Venules, mm/s; mean (SD)	3.11 (0.46)	3.23 (0.52)	2.76 (0.50)	2.75 (0.53)	2.80 (0.45)	0.064^a	0.003 ^b	0.005 ^b	0.048 ^b	0.48^b

HC = healthy control; OD = right; OS = left; MS = multiple sclerosis; MSNON = multiple sclerosis without optic neuritis; MSON = multiple sclerosis with optic neuritis; SD = standard deviation
^aPaired t-test
^bMixed-effects linear regression adjusted for age, sex, and within-subject inter-eye correlations in HCs (as well as disease duration between the MS groups)
P ≤ 0.05 indicates significance

ISSN: 2326-0254