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Table 2 Outcomes reported in literature for epi-on CXL procedures (2010–2015)

From: Collagen cross-linking: when and how? A review of the state of the art of the technique and new perspectives

Author (Year)

Follow-up

Results

Design

Number of Eyes

Indication

  

Kmax

Mean Keratometry

BCVA

   

Lensiak SP et al. (2014) [81]

6 months

S

 

S

PCS

25

Keratoconous

De Bernardo M et al. (2014) [82]

6 months

S

 

I

PCS

36

Keratoconus

Khairy HA et al. (2014) [83]

1 year

D

 

S

PCS

32

Keratoconus

Salman AG (2013) [84]

1 year

S

 

S

PC

22

Pediatric Keratoconus

Caporossi A et al. (2013) [85]

2 years

W

 

S

PCS

26

Keratoconus

Buzzonetti L et al. (2012) [86]

18 months

 

W

I

PCS

13

Pediatric Keratoconus

Spadea L et al. (2012) [87]

1 year

D

 

I

PCS

16

Keratoconus

Filippello M et al. (2012) [88]

18 months

D

 

I

PC

20

Keratoconus

Leccisotti A et al. (2011) [89]

1 year

S

 

I

RCT

51

Keratoconus

  1. S= Stabilized, D= Significantly decreased, I= Significantly improved, W= worsened, PCS= Prospective case series, RCT= Randomized controlled trial, PC= Prospective comparative