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Fig. 1 | Eye and Vision

Fig. 1

From: Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies

Fig. 1

Schematic diagram of gallic acid treating dry eye through its anti-inflammatory and antioxidant effects. LPS, lipopolysaccharide; CD-14, clusterdifferentiation-14; MD-2, myeloid differentiation protein-2; TLR4, toll like receptor 4; IκB, inhibitor of NF-κB; P, phosphorylated; NF-κB P65, nuclear factor kappa-B P65; IL-6, interleukin 6; TNF-α, tumor necrosis factor alpha; NO, nitric oxide; ROS, reactive oxygen species; Keap1, Kelch-like ECH-associated protein 1; Nrf2, nuclear factor E2-relate factor-2; ARE, antioxidant response elements; HO-1, heme oxygenase-1; NQO-1, NADPH quinineoxidoreductase-1

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