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Table 3 Results from ROC curve analysis of patients vs. controls classification based on AULCSF, inner retinal microvascular density and GCCL thickness

From: Reduced contrast sensitivity function correlated with superficial retinal capillary plexus impairment in early stage of dysthyroid optic neuropathy

Parameters

non-DON

DON

AUC

Cutoff

Sensitivity (%)

Specificity (%)

AUC

Cutoff

Sensitivity (%)

Specificity (%)

AULCSF

0.831

1.22

87.5

70.0

0.987

1.17

91.7

88.4

SRCP density (%)

0.639

45.10

87.5

38.0

0.921

44.57

95.8

83.9

DRCP density (%)

0.585

48.91

79.2

40.0

0.667

49.04

75.0

61.3

GCCL thickness (μm)

0.473

100.50

66.7

20.0

0.673

97.70

83.3

45.2

  1. DON = dysthyroid optic neuropathy; non-DON = TAO patients without clinical signs of DON; TAO = thyroid-associated ophthalmopathy; AULCSF = area under the log contrast sensitivity function; SRCP = superficial retinal capillary plexus; DRCP = deep retinal capillary plexus; GCCL = ganglion cell complex layer; ROC = receiver operating characteristic; AUC = areas under the ROC curve
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Eye and Vision

ISSN: 2326-0254