Skip to main content
Fig. 5 | Eye and Vision

Fig. 5

From: Regional differences of the sclera in the ocular hypertensive rat model induced by circumlimbal suture

Fig. 5

Paradigm for the central scleral change involved in circumlimbal suture associated eyes with ocular hypertension. a The ganglion cell complex (GCC) thins followed by scleral thinning that results from extracellular matrix (ECM) remodeling during suture-related stimulus; b These suture-related pressure signals increase the fibroblasts’ response to increase αSMA expression and decrease collagen production after 2 weeks of the operation. Central scleral ECM remodeling with elevated intraocular pressure (IOP) from suture-related stress after 2 weeks of the operation, leading to increased collagen production and decreased expression of αSMA

Back to article page

Eye and Vision

ISSN: 2326-0254