Fig. 1

Study scheme, results of axial length (AL), and retinal ganglion cells (RGCs) in ocular hypertension eyes. a Schematic of the experimental time points; b Verifying elongated AL measured by ultrasound in circumlimbal suture (CS) models at 3 days before the operation, 7, 14, 21, and 28 days after the operation (n = 6, **P < 0.01 compared with the control group, **P < 0.01 compared with sclerosant injection (SI) group at 21 and 28 days after the operation). c Verifying changes of diopters in CS eyes at 3 days before the operation, 7, 14, 21, and 28 days around the perioperative period (n = 6, *P < 0.05 compared with the control group at 7 and 14 days after the operation, *P < 0.05 compared with SI group at 7 days after the operation); d The mean density of RGCs (MD-RGCs) retrogradely labeled by fluorogold after 28 days of operation in the CS rats (n = 6, **P < 0.01 compared with the control group in the peripheral, mid-peripheral and central retina, *P < 0.05 compared with SI group in the peripheral, mid-peripheral and central retina). Scale bar = 50 μm