Wide-field swept-source OCT angiography of the periarterial capillary-free zone before and after anti-VEGF therapy for branch retinal vein occlusion

Table 3 Comparison of paCFZ parameters in the first- and second-order arteries in ischemic and nonischemic BRVO at baseline and 12 months after anti-VEGF treatment

Parameters	BL		P*	12 m		P*	P (BL vs. 12 m)**
Parameters	iBRVO (n = 36)	NiBRVO (n = 18)	P*	iBRVO (n = 36)	NiBRVO (n = 18)	P*	iBRVO (n = 36)	NiBRVO (n = 18)
First-order
PaCFZ area (mm²)	0.55 ± 0.18	0.53 ± 0.20	0.74	0.43 ± 0.18	0.43 ± 0.19	0.99	< 0.01	< 0.01
Artery area (mm²)	0.47 ± 0.18	0.52 ± 0.18	0.44	0.47 ± 0.18	0.51 ± 0.18	0.39	0.06	0.28
P/A ratio	1.19 ± 0.21	1.04 ± 0.20	0.02	0.92 ± 0.16	0.81 ± 0.16	0.04	< 0.01	< 0.01
Second-order
PaCFZ area (mm²)	1.01 ± 0.54	0.85 ± 0.34	0.24	0.77 ± 0.42	0.66 ± 0.27	0.30	< 0.01	< 0.01
Artery area (mm²)	0.58 ± 0.38	0.63 ± 0.38	0.62	0.56 ± 0.37	0.65 ± 0.38	0.45	0.08	0.43
P/A ratio	1.96 ± 0.52	1.57 ± 0.53	0.01	1.55 ± 0.48	1.20 ± 0.46	0.01	< 0.01	< 0.01

paCFZ = periarterial capillary-free zone; BRVO = branch retinal vein occlusion; VEGF = vascular endothelial growth factor; BL = baseline; iBRVO = ischemic branch retinal vein occlusion; NiBRVO = non-ischemic branch retinal vein occlusion; P/A = paCFZ area to artery area
*Unpaired t-test
**Paired t-test

ISSN: 2326-0254