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Table 3 Comparison of paCFZ parameters in the first- and second-order arteries in ischemic and nonischemic BRVO at baseline and 12 months after anti-VEGF treatment

From: Wide-field swept-source OCT angiography of the periarterial capillary-free zone before and after anti-VEGF therapy for branch retinal vein occlusion

Parameters BL P* 12 m P* P (BL vs. 12 m)**
iBRVO (n = 36) NiBRVO (n = 18) iBRVO (n = 36) NiBRVO (n = 18) iBRVO (n = 36) NiBRVO (n = 18)
First-order
 PaCFZ area (mm2) 0.55 ± 0.18 0.53 ± 0.20 0.74 0.43 ± 0.18 0.43 ± 0.19 0.99 < 0.01 < 0.01
 Artery area (mm2) 0.47 ± 0.18 0.52 ± 0.18 0.44 0.47 ± 0.18 0.51 ± 0.18 0.39 0.06 0.28
 P/A ratio 1.19 ± 0.21 1.04 ± 0.20 0.02 0.92 ± 0.16 0.81 ± 0.16 0.04 < 0.01 < 0.01
Second-order
 PaCFZ area (mm2) 1.01 ± 0.54 0.85 ± 0.34 0.24 0.77 ± 0.42 0.66 ± 0.27 0.30 < 0.01 < 0.01
 Artery area (mm2) 0.58 ± 0.38 0.63 ± 0.38 0.62 0.56 ± 0.37 0.65 ± 0.38 0.45 0.08 0.43
 P/A ratio 1.96 ± 0.52 1.57 ± 0.53 0.01 1.55 ± 0.48 1.20 ± 0.46 0.01 < 0.01 < 0.01
  1. paCFZ = periarterial capillary-free zone; BRVO = branch retinal vein occlusion; VEGF = vascular endothelial growth factor; BL = baseline; iBRVO = ischemic branch retinal vein occlusion; NiBRVO = non-ischemic branch retinal vein occlusion; P/A = paCFZ area to artery area
  2. *Unpaired t-test
  3. **Paired t-test