Table 3 Linear regression analysis of the associations of the 12-month axial length change with basic and ocular characteristics

From: Weighted Zernike defocus coefficient of treatment zone is a meaningful indicator for myopia control efficacy of Ortho-K lenses

Parameters	Univariate regression			Multivariate regression**
Parameters	R	Beta (95% CI)	P value	Beta (95% CI)	P value	Standardized beta
Age (years)	0.437	− 0.047 (− 0.064 to − 0.031)	< 0.001	− 0.035 (− 0.051 to − 0.020)	0.001	− 0.325
Sex, male	0.085	0.037 (− 0.038 to 0.112)	0.328
C_{weighted defocus} (D/mm²)	0.445	− 0.581 (− 0.784 to 0.379)	< 0.001	− 0.510 (− 0.732 to − 0.288)	0.001	− 0.391
Horizontal decentration (mm)	0.170	− 0.069 (− 0.138 to 0.001)	0.050	− 0.040 (− 0.096 to 0.015)	0.156	− 0.99
Vertical decentration (mm)	0.007	0.004 (− 0.091 to 0.098)	0.941
SE (D)	0.201	0.027 (0.004 to 0.049)	0.020	− 0.018 (− 0.041 to 0.004)	0.107	− 0.139
Pupil diameter (mm)	0.400	− 0.151 (− 0.210 to − 0.091)	< 0.001	− 0.094 (− 0.148 to − 0.041)	0.001	− 0.250
Mean K (D)	0.009	0.001 (− 0.026 to 0.029)	0.920
HVID (mm)	0.058	0.030 (− 0.058to 0.117)	0.853
E value	0.003	− 0.006 (− 0.378 to 0.365)	0.973
ACD (mm)	0.112	− 0.114 (− 0.289 to 0.061)	0.211

SE = spherical equivalent; K = keratometry; HVID = horizontal visible iris diameter; ACD = anterior chamber depth; CI = confidence interval
**Inclusion of variables: age, C_{weighted defocus}, horizontal decentration, pupil diameter, SE (R = 0.636, R² = 0.405, Adjusted R² = 0.381, P < 0.001)

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