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Table 3 Linear regression analysis of the associations of the 12-month axial length change with basic and ocular characteristics

From: Weighted Zernike defocus coefficient of treatment zone is a meaningful indicator for myopia control efficacy of Ortho-K lenses

  Parameters Univariate regression Multivariate regression**
R Beta (95% CI) P value Beta (95% CI) P value Standardized beta
Age (years) 0.437 − 0.047 (− 0.064 to − 0.031)  < 0.001 − 0.035 (− 0.051 to − 0.020) 0.001 − 0.325
Sex, male 0.085 0.037 (− 0.038 to 0.112) 0.328    
Cweighted defocus (D/mm2) 0.445 − 0.581 (− 0.784 to 0.379)  < 0.001 − 0.510 (− 0.732 to − 0.288) 0.001 − 0.391
Horizontal decentration (mm) 0.170 − 0.069 (− 0.138 to 0.001) 0.050 − 0.040 (− 0.096 to 0.015) 0.156 − 0.99
Vertical decentration (mm) 0.007 0.004 (− 0.091 to 0.098) 0.941    
SE (D) 0.201 0.027 (0.004 to 0.049) 0.020 − 0.018 (− 0.041 to 0.004) 0.107 − 0.139
Pupil diameter (mm) 0.400 − 0.151 (− 0.210 to − 0.091)  < 0.001 − 0.094 (− 0.148 to − 0.041) 0.001 − 0.250
Mean K (D) 0.009 0.001 (− 0.026 to 0.029) 0.920    
HVID (mm) 0.058 0.030 (− 0.058to 0.117) 0.853    
E value 0.003 − 0.006 (− 0.378 to 0.365) 0.973    
ACD (mm) 0.112 − 0.114 (− 0.289 to 0.061) 0.211    
  1. SE = spherical equivalent; K = keratometry; HVID = horizontal visible iris diameter; ACD = anterior chamber depth; CI = confidence interval
  2. **Inclusion of variables: age, Cweighted defocus, horizontal decentration, pupil diameter, SE (R = 0.636, R2 = 0.405, Adjusted R2 = 0.381, P < 0.001)