Fig. 6
From: Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice
DNA damage in MMS-treated mouse retinas. a Representative images of DNA damage staining in retinal cross sections from each group before and 1, 3, and 7 days after MMS injection. b Semi-quantification of DNA damage staining in each group using ImageJ. The C3−/− mouse group significantly showed fewer DNA damage-positive cells in the retina than the wild-type (WT) mouse group (n = 6, ***P < 0.001 compared with control). MMS, methyl methane sulfonate; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; ONL, outer nuclear layer