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Fig. 7 | Eye and Vision

Fig. 7

From: The ghrelin-GHSR-1a pathway inhibits high glucose-induced retinal angiogenesis in vitro by alleviating endoplasmic reticulum stress

Fig. 7

Representative Western blotting images of PERK, p-PERK, ATF4, and CHOP in human retinal microvascular endothelial cells (HRMECs) at 48 h of treatment in different groups (a, b), and the relative expression of PERK (c), p-PERK (d), ATF4 (e), and CHOP (f) after normalization by GAPDH (n = 3, *P < 0.05 vs. C group; #P < 0.05 vs. HG group; &P < 0.05 vs. ghrelin group; @P < 0.05 vs. ghrelin + siGHSR-1a group). C, control; HG, high glucose; siGHSR-1a, cells transfected with GHSR-1a-specific siRNA; NC-siGHSR-1a, cells transfected with nonspecific sequence (negative control) of siGHSR-1a; GAPDH, glyceraldehyde-3-phosphate dehydrogenase

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Eye and Vision

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