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Table 1 Summary of baseline visit visual acuity data and ulcer size, epithelization times in both treatment groups, and mean follow-up time and visual acuities at discharge visit

From: PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial

Baseline visit

Medication group (n = 21)

PACK-CXL group (n = 18)

P-value

Mean (SD)

Mean (SD)

Ulcer size (mm)

2.33 (0.87)

2.75 (1.07)

0.1564

UCVA (logMAR)

1.15 (1.03)

1.24 (0.90)

0.494

CDVA (logMAR)

0.73 (0.85)

0.76 (0.66)

0.453

Epithelization time (days)

Medication group (n = 19)

PACK-CXL group (n = 16)

P-value

Median

7

7

0.828

Q75%

20.5

10

 

Q90%

37

19.6

 

Maximum

50

28

 

Mean (SD)

14.58 (14.95)

9.94 (7.18)

 

Epithelization time difference between both groups

Difference (PACK-CXL-med)

− 4.64

  

Pooled SD

12.06

  

Error margin

8.02

  

CI (95%)

(− 12.66, 3.38)

  

Discharge visit

Medication group (n = 19)

PACK-CXL group (n = 16)

P-value

Mean (SD)

Mean (SD)

Therapy/follow-up duration (days)

29.42 (12.60)

22.56 (3.82)

 

UCVA (logMAR)

1.00 (1.06)

0.79 (0.68)

0.96

CDVA (logMAR)

0.54 (0.75)

0.53 (0.68)

0.96

  1. UCVA uncorrected visual acuity; CDVA corrected distance visual acuity; logMAR logarithm of the minimum angle of resolution; med medication group, PACK-CXL photoactivated chromophore corneal cross-linking; SD standard deviation; CI confidence interval