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Fig. 4 | Eye and Vision

Fig. 4

From: PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial

Fig. 4

Time course of corneal ulcers in the PACK-CXL group. a Patient presenting with a large corneal ulcer in the left nasal inferior cornea. b Marked reduction of the epithelial defect and beginning reorganization at day 7 after PACK-CXL. c Completed epithelial closure and beginning scar formation. d Round and opaque ulcer in the left upper temporal cornea. e At day 7 after PACK-CXL, the opacity starts resolving from the temporal edge. Of note, there is a slight transient clinical worsening of the temporal lesion border due to the Jarisch–Herxheimer reaction. f At 28 days after PACK-CXL, infiltrate regression and full epithelial closure with beginning scar formation are noted. PACK-CXL photoactivated chromophore corneal cross-linking

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Eye and Vision

ISSN: 2326-0254