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Table 2 Eight-year outcomes in intraocular pressure, glaucoma medication use, and best-corrected visual acuity

From: Long-term outcomes of two first-generation trabecular micro-bypass stents (iStent) with phacoemulsification in primary open-angle glaucoma: eight-year results

Variable N Mean % Change vs. baseline Mean change vs. baseline P value
IOP (mmHg)
 Preoperative 62 19.2 ± 3.9    
 POM1 62 15.4 ± 3.5  − 19.8  − 3.8  < 0.001**
 POM6 57 15.5 ± 3.4  − 19.3  − 3.7  < 0.001**
 POY1 59 15.8 ± 3.0  − 17.7  − 3.4  < 0.001**
 POY2 57 15.7 ± 3.1  − 18.2  − 3.5  < 0.001**
 POY3 54 15.7 ± 3.0  − 18.2  − 3.5  < 0.001**
 POY4 53 14.9 ± 2.6  − 22.4  − 4.3  < 0.001**
 POY5 53 14.6 ± 2.8  − 24.0  − 4.6  < 0.001**
 POY6 51 14.8 ± 2.7  − 22.9  − 4.4  < 0.001**
 POY7 56 14.9 ± 3.1  − 22.4  − 4.3  < 0.001**
 POY8 56 14.2 ± 2.4  − 26.0  − 5.0  < 0.001**
Number of glaucoma medications
 Preoperative 62 2.8 ± 1.1    
 POM1 62 0.9 ± 1.3  − 67.9  − 1.9  < 0.001**
 POM6 58 1.2 ± 1.2  − 57.1  − 1.5  < 0.001**
 POY1 58 1.3 ± 1.2  − 53.6  − 1.5  < 0.001**
 POY2 57 1.5 ± 1.2  − 46.4  − 1.3  < 0.001**
 POY3 55 1.6 ± 1.3  − 42.9  − 1.1  < 0.001**
 POY4 55 1.9 ± 1.3  − 32.1  − 0.9  < 0.001**
 POY5 55 2.1 ± 1.2  − 25.0  − 0.8  < 0.001**
 POY6 56 2.2 ± 1.2  − 21.4  − 0.6  < 0.001**
 POY7 56 2.3 ± 1.2  − 17.9  − 0.6 0.002*
 POY8 56 2.3 ± 1.2  − 17.9  − 0.5 0.006*
BCVA (logMAR)
 Preoperative 62 0.17 ± 0.15    
 POM1 62 0.11 ± 0.10  − 35.3  − 0.06  < 0.001**
 POM6 57 0.10 ± 0.19  − 41.2  − 0.07  < 0.001**
 POY1 56 0.09 ± 0.11  − 47.1  − 0.08  < 0.001**
 POY2 58 0.07 ± 0.10  − 58.8  − 0.10  < 0.001**
 POY3 53 0.07 ± 0.10  − 58.8  − 0.10  < 0.001**
 POY4 52 0.08 ± 0.11  − 52.9  − 0.09  < 0.001**
 POY5 53 0.06 ± 0.09  − 64.7  − 0.11  < 0.001**
 POY6 51 0.09 ± 0.11  − 47.1  − 0.08  < 0.001**
 POY7 55 0.12 ± 0.12  − 29.4  − 0.05 0.014*
 POY8 56 0.11 ± 0.14  − 35.3  − 0.06 0.015*
  1. Mean ± standard deviations are presented and statistically compared to preoperative values using Generalized Estimating Equations with sequential Bonferroni correction for multiple comparisons
  2. IOP intraocular pressure; BCVA best-corrected visual acuity; POM postoperative month; POY postoperative year
  3. Statistical significance is denoted by * for P < 0.05 and ** for P < 0.001