|
Adverse effect
|
RD
|
95% CI
|
P
|
|---|
|
Keratoconus progression
|
− 0.025
|
− 0.059 – 0.008
|
0.141
|
|
Delay in epithelial healing
|
0.049
|
0.0030 – 0.0946
|
0.035*
|
|
Persistent stromal haze
|
0.0525
|
0.0063 – 0.0986
|
0.026*
|
|
Sterile infiltrates
|
0.0036
|
− 0.0206 – 0.0279
|
0.768
|
|
Infection
|
0.0036
|
− 0.0206 – 0.0279
|
0.768
|
- CI confidence interval; RD risk difference
- If the value of the summary effect is negative, epi-on corneal collagen cross-linking would have more risk of adverse effects. Otherwise, epi-off would have this condition. All the results were obtained through fixed-effects models due to the lack of heterogeneity
- *Indicates statistical significance
