Genetic mutations and molecular mechanisms of Fuchs endothelial corneal dystrophy

Table 2 Mutations of TCF8 (ZEB1) gene on chromosome 10p11.22 and changes in its protein domain

Gene	Nucleotide change	Amino acid change	References
TCF8 (ZEB1)	c.2522A > C	p.Q841P	[38]
	c.619A > G	p.S207G	[38]
	c.192T > C	p.D64D	[37, 39]
	NA	p.T232T	[39]
	c.2197G > A	p.E733K	[39]
	c.2453C > T	p.A818V	[39]
	c.2840 T > A	p.L947stop	[39]
	NA	p.S234S	[39]
	c.2519A > C	p.Q840P	[11, 39]
	c.2087A > G	p.N696S	[37]
	c.232A > G	p.N78T	[11]
	c.1945C > G	p.P649A	[11]
	c.2429A > C	p.Q810P	[11]
	c.2714C > G	p.A905G	[11]
	c.666 T > C	p.S201S	[19]
	c.852 T > C	p.S263S	[19]
	c.1721A > G	p.K553R	[19]
	c.1738C > T	p.P559S	[19]
	c.2037C > G	p.N658K	[19]
	c.2124A > C	p.P687P	[19]
	c.2623C > A	p.Q854K	[19]

ISSN: 2326-0254