| |
Healthy
|
Keratoconus
|
P value
|
Mild KC
|
Moderate KC
|
Advanced KC
|
P value*
|
P value†
|
P value‡
|
|---|
|
ARTh
|
533 ± 95
|
236 ± 126
|
< 0.001
|
348 ± 128
|
227 ± 75
|
132 ± 50
|
< 0.001
|
< 0.001
|
< 0.001
|
|
InverseR (mm-1)
|
0.17 ± 0.04
|
0.23 ± 0.04
|
< 0.001
|
0.20 ± 0.02
|
0.23 ± 0.03
|
0.26 ± 0.04
|
< 0.001
|
< 0.001
|
< 0.001
|
|
SPA1 (mmHg/mm)
|
109.5 ± 15.3
|
68.9 ± 18.9
|
< 0.001
|
82.6 ± 13.5
|
69.3 ± 15.6
|
54.5 ± 16.0
|
< 0.001
|
< 0.001
|
< 0.001
|
|
Pachyslope (μm)
|
43.1 ± 8.1
|
72.8 ± 29.5
|
< 0.001
|
52.6 ± 12.7
|
69.2 ± 19.4
|
97.1 ± 33.0
|
0.003
|
< 0.001
|
< 0.001
|
|
Pachy (μm)
|
564 ± 26
|
487 ± 42
|
< 0.001
|
513 ± 30
|
491 ± 34
|
458 ± 43
|
< 0.001
|
< 0.001
|
< 0.001
|
|
IntInversR (mm-1)
|
8.2 ± 1.1
|
11.7 ± 2.5
|
< 0.001
|
9.8 ± 1.3
|
11.7 ± 1.6
|
13.8 ± 2.5
|
< 0.001
|
< 0.001
|
< 0.001
|
|
DAR2 (mm)
|
4.20 ± 0.44
|
5.76 ± 1.14
|
< 0.001
|
4.98 ± 0.61
|
5.66 ± 0.73
|
6.64 ± 1.30
|
< 0.001
|
< 0.001
|
< 0.001
|
|
DAR1 (mm)
|
1.57 ± 0.06
|
1.71 ± 0.08
|
< 0.001
|
1.65 ± 0.06
|
1.71 ± 0.07
|
1.76 ± 0.08
|
< 0.001
|
< 0.001
|
< 0.001
|
|
Radius (mm)
|
7.27 ± 0.83
|
5.66 ± 0.96
|
< 0.001
|
6.43 ± 0.74
|
5.59 ± 0.69
|
4.95 ± 0.82
|
< 0.001
|
< 0.001
|
< 0.001
|
|
A1DefA (mm)
|
0.10 ± 0.01
|
0.11 ± 0.02
|
< 0.001
|
0.10 ± 0.01
|
0.11 ± 0.01
|
0.12 ± 0.02
|
0.151
|
0.002
|
< 0.001
|
- * Between Healthy and mild KC; † Between mild KC and moderate KC; ‡ Between moderate KC and advanced KC. A1 applanation 1; ARTh Ambrosio relational thickness horizontal; DAR1/2 ratio of central and peripheral deformation at 1/2 mm; DefA deflection amplitude; InverseR inverse concave radius; IntInversR integrated inverse (concave) radius, Pachy corneal thickness measured by Corvis ST; Radius anterior corneal curvature from 2-dimensional corneal cross-section by Corvis ST; SPA1 stiffness parameter at 1st applanation. Bold type signifies P < 0.05
