Table 1 Demographics of healthy and keratoconus subjects

N

116

318

N.A.

106

108

104

Eye (right/left)

64/52

171/147

0.796

58/48

59/49

54/50

Gender (male/female)

74/42

246/72

0.004

76/30

83/25

87/17

Age (years)

29.3 ± 7.1

33.1 ± 8.1

< 0.001

33.4 ± 8.1

32.7 ± 7.0

33.2 ± 9.1

0.001

1.0

1.0

Km (D)

43.1 ± 1.3

46.9 ± 3.7

< 0.001

44.1 ± 1.7

46.7 ± 2.8

50.1 ± 3.1

0.023

< 0.001

< 0.001

ISV

21.1 ± 9.0

77.9 ± 34.8

< 0.001

40.3 ± 7.3

73.2 ± 9.5

121.0 ± 14.9

< 0.001

< 0.001

< 0.001

Normative range ²⁷

N.A.

N.A.

N.A.

30–55

55–90

90–150

N.A.

N.A.

N.A.

KI

1.01 ± 0.02

1.21 ± 0.11

< 0.001

1.09 ± 0.03

1.19 ± 0.04

1.35 ± 0.07

< 0.001

< 0.001

< 0.001

Normative range ²⁷

N.A.

N.A.

N.A.

1.07–1.15

1.10–1.25

1.15–1.45

N.A.

N.A.

N.A.

Rmin (mm)

7.58 ± 0.26

6.33 ± 0.68

< 0.001

7.05 ± 0.28

6.29 ± 0.36

5.63 ± 0.40

< 0.001

< 0.001

< 0.001

Normative range ²⁷

N.A.

N.A.

N.A.

7.5–6.5

6.9–5.3

6.6–4.8

N.A.

N.A.

N.A.

Kmax (D)

44.6 ± 1.5

53.9 ± 5.9

< 0.001

48.0 ± 1.9

53.9 ± 3.1

60.2 ± 4.2

< 0.001

< 0.001

< 0.001

I-S value (D)

−0.26 ± 0.7

5.7 ± 3.2

< 0.001

2.6 ± 1.2

5.4 ± 1.4

9.4 ± 2.2

< 0.001

< 0.001

< 0.001

ARC (mm)

7.8 ± 0.2

6.9 ± 0.59

< 0.001

7.4 ± 0.3

6.9 ± 0.3

6.2 ± 0.4

< 0.001

< 0.001

< 0.001

PRC (mm)

6.4 ± 0.2

5.2 ± 0.6

< 0.001

5.8 ± 0.3

5.2 ± 0.3

4.6 ± 0.4

< 0.001

< 0.001

< 0.001

TCT (μm)

560 ± 24

475 ± 44

< 0.001

505 ± 31

478 ± 34

441 ± 39

< 0.001

< 0.001

< 0.001

BAD-D

0.6 ± 0.5

7.4 ± 3.8

< 0.001

3.9 ± 1.0

6.8 ± 1.6

11.6 ± 3.1

< 0.001

< 0.001

< 0.001

bIOP (mmHg)

15.2 ± 2.2

14.3 ± 2.1

< 0.001

14.5 ± 1.7

14.4 ± 2.1

14.1 ± 2.4

0.099

1.0

1.0

CBI

0.04 ± 0.10

0.86 ± 0.30

< 0.001

0.66 ± 0.40

0.93 ± 0.20

0.99 ± 0.00

< 0.001

< 0.001

0.224

TBI

0.08 ± 0.13

0.99 ± 0.04

< 0.001

0.99 ± 0.07

0.99 ± 0.00

0.99 ± 0.00

< 0.001

1.0

1.0