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Table 3 Predictive factors on the change of BCVA

From: Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy

 

Univariate model

Multivariate model

Estimate (95% CI)

P value

Estimate (95% CI)

P value

Baseline age, per year older

−0.01 (−0.03, 0.00)

0.139

Gender: Male

0.17 (−0.14, 0.46)

0.294

Smoking history: never

0.17 (−0.51, 0.84)

0.632

TSH level, per 1 uIU/ml higher

−0.02 (−0.04, 0.00)

0.083

BMI, per 1 higher

−0.01 (−0.07, 0.05)

0.719

  

IVGC therapy: never

−0.11 (−0.45, 0.23)

0.524

Duration of DON, per month longer

0.00 (0.00, 0.00)

0.944

Preop. CAS, per 1 score higher

−0.05 (−0.18, 0.06)

0.928

Medium rectus diameter, per 1 mm thicker

0.08 (0.02, 0.13)

0.008**

0.07 (0.01, 0.13)

0.019*

Preop. BCVA, per 0.1 LogMAR higher

0.08 (0.07, 0.09)

< 0.001***

0.08 (0.07, 0.09)

< 0.001***

Preop. MD, per 1 dB greater

0.03 (0.04, −0.01)

< 0.001***

−0.04 (−0.05, −0.02)

< 0.001***

Preop. exophthalmos, per 1 mm higher

0.04(0.00, 0.09)

0.051

  1. Confounding factors including age, gender, body mass Index, duration of DON and smoking history were adjusted for
  2. Values with statistical significance are shown in bold
  3. BCVA= best-corrected visual acuity, TSH= thyroid stimulating hormone, BMI= body mass index, IVGC= intravenous glucocorticoid, DON= dysthyroid optic neuropathy, CAS= clinical activity score, MD= mean deviation
  4. *P < 0.05; **P < 0.01; ***P < 0.001