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Table 3 Predictive factors on the change of BCVA

From: Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy

  Univariate model Multivariate model
Estimate (95% CI) P value Estimate (95% CI) P value
Baseline age, per year older −0.01 (−0.03, 0.00) 0.139
Gender: Male 0.17 (−0.14, 0.46) 0.294
Smoking history: never 0.17 (−0.51, 0.84) 0.632
TSH level, per 1 uIU/ml higher −0.02 (−0.04, 0.00) 0.083
BMI, per 1 higher −0.01 (−0.07, 0.05) 0.719   
IVGC therapy: never −0.11 (−0.45, 0.23) 0.524
Duration of DON, per month longer 0.00 (0.00, 0.00) 0.944
Preop. CAS, per 1 score higher −0.05 (−0.18, 0.06) 0.928
Medium rectus diameter, per 1 mm thicker 0.08 (0.02, 0.13) 0.008** 0.07 (0.01, 0.13) 0.019*
Preop. BCVA, per 0.1 LogMAR higher 0.08 (0.07, 0.09) < 0.001*** 0.08 (0.07, 0.09) < 0.001***
Preop. MD, per 1 dB greater 0.03 (0.04, −0.01) < 0.001*** −0.04 (−0.05, −0.02) < 0.001***
Preop. exophthalmos, per 1 mm higher 0.04(0.00, 0.09) 0.051
  1. Confounding factors including age, gender, body mass Index, duration of DON and smoking history were adjusted for
  2. Values with statistical significance are shown in bold
  3. BCVA= best-corrected visual acuity, TSH= thyroid stimulating hormone, BMI= body mass index, IVGC= intravenous glucocorticoid, DON= dysthyroid optic neuropathy, CAS= clinical activity score, MD= mean deviation
  4. *P < 0.05; **P < 0.01; ***P < 0.001