Fig. 6
From: Anti-VEGF therapy prevents Müller intracellular edema by decreasing VEGF-A in diabetic retinopathy
Expression of VEGF-A increased in rMC-1 cells when treated with glyoxal. The (a) mRNA and (b) protein level of VEGF-A in glyoxal-treated rMC-1 cells for 12 and 24 h. c The concentration of VEGF-A in the supernatant of glyoxal-treated rMC-1 cells with or without ranibizumab. Data are expressed as mean ± SE (n = 6 in [a], n = 3 in [b], n = 4 in [c], *P < 0.05). N: normal control; G: rMC-1 cells treated with 1 mM glyoxal; G + R: rMC-1 cells treated with glyoxal and ranibizumab