Fig. 10
From: Anti-VEGF therapy prevents Müller intracellular edema by decreasing VEGF-A in diabetic retinopathy
Ranibizumab decreased intracellular osmotic pressure by sodium efflux. a Intracellular potassium and (b) sodium levels were detected in glyoxal-treated rMC-1 cell with or without ranibizumab. c Protein expression of Na+-K+-ATPase in glyoxal-treated rMC-1 cells treated with or without ranibizumab. Data are expressed as mean ± SE (n = 10 in [a, b], n = 4 in [c], *P < 0.05). N: normal control; G: rMC-1 cells treated with 1 mM glyoxal; G + R: rMC-1 cells treated with glyoxal and ranibizumab