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Table 1 Intergroup differences of all measured parameters among normal, KC, and suspected KC groups

From: Relationship between corneal biomechanical parameters and corneal sublayer thickness measured by Corvis ST and UHR-OCT in keratoconus and normal eyes

Parameter Mean ± SD ANOVA Normal vs. KC
P
Normal vs. SKC
P
Normal
(n = 17)
KC
(n = 25)
SKC
(n = 52)
Age (years) 23.44 ± 2.00 25.11 ± 7.36 23.70 ± 5.85 0.629 0.63 0.972
Gender (M/F) 10/7 11/8 14/20
Cylinder (D) −0.65 ± 0.56 −3.41 ± 2.29 −0.77 ± 0.61 0.000a 0.000a 0.933
SE (D) −3.98 ± 3.41 −4.25 ± 2.89 −4.97 ± 2.02 0.280 0.944 0.353
A1V (m/s) 0.15 ± 0.02 0.16 ± 0.03 0.15 ± 0.02 0.021a 0.213 0.841
A2V (m/s) −0.38 ± 0.04 −0.352 ± 0.09 −0.34 ± 0.04 0.069 0.244 0.055
PD (mm) 4.90 ± 0.22 4.82 ± 0.23 4.82 ± 0.24 0.428 0.541 0.409
HCR (mm) 6.81 ± 0.60 5.36 ± 0.76 6.64 ± 0.52 0.000a 0.000a 0.550
HCDfA (mm) 1.10 ± 0.10 1.14 ± 0.12 1.07 ± 0.09 0.018a 0.430 0.508
SP-A1 107.05 ± 15.84 71.67 ± 17.34 99.49 ± 12.66 0.000a 0.000a 0.203
IR 8.78 ± 0.88 12.41 ± 2.43 9.38 ± 0.90 0.000a 0.000a 0.316
ARTh 412.88 ± 64.94 206.41 ± 80.57 363.70 ± 50.89 0.000a 0.000a 0.016a
DA ratio 4.37 ± 0.37 5.55 ± 0.85 4.47 ± 0.43 0.000a 0.000a 0.816
TBIb 0.17 ± 0.15 1.00 0.49 ± 0.28 0.000a 0.004a
CBIb 0.13 ± 0.18 0.99 ± 0.04 0.23 ± 0.30 0.000a 1.000
Flat K (D)b 42.52 ± 0.97 45.27 ± 2.47 43.20 ± 1.34 0.000a 0.019a
Steep K (D) 43.56 ± 1.29 48.67 ± 3.43 44.41 ± 1.43 0.000a 0.000a 0.015a
EPT (μm) 53.53 ± 2.00 48.17 ± 3.16 53.52 ± 2.26 0.000a 0.000a 0.936
BLT (μm) 17.96 ± 1.58 15.69 ± 1.32 16.12 ± 1.19 0.000a 0.000a 0.000a
STT (μm) 480.65 ± 32.01 414.10 ± 29.43 460.57 ± 33.89 0.000a 0.000a 0.074
  1. Normal = normal group; KC = keratoconus group; SKC = suspected keratoconus group; n = number of eyes; Cylinder = cylindrical power; SE = spherical equivalent; A1V = corneal apex velocity at first applanation; A2V = corneal apex velocity at second applanation; PD = peak distance; HCR = highest concavity radius of curvature; HCDfA = deflection amplitude at highest concavity; SP-A1 = stiffness parameter at first applanation; IR = integrated radius; ARTh = Ambrosio relational thickness to the horizontal profile; DA = deformation amplitude; TBI = tomographic and biomechanical index; CBI = Corvis biomechanical index; Flat K = flat keratometry; Steep K = steep keratometry; EPT = epithelial thickness; BLT = Bowman’s layer thickness; STT = stromal thickness; D = diopter; aP < 0.05; bKruskal-Wallis test