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Table 1 Intergroup differences of all measured parameters among normal, KC, and suspected KC groups

From: Relationship between corneal biomechanical parameters and corneal sublayer thickness measured by Corvis ST and UHR-OCT in keratoconus and normal eyes

Parameter

Mean ± SD

ANOVA

Normal vs. KC

P

Normal vs. SKC

P

Normal

(n = 17)

KC

(n = 25)

SKC

(n = 52)

Age (years)

23.44 ± 2.00

25.11 ± 7.36

23.70 ± 5.85

0.629

0.63

0.972

Gender (M/F)

10/7

11/8

14/20

–

–

–

Cylinder (D)

−0.65 ± 0.56

−3.41 ± 2.29

−0.77 ± 0.61

0.000a

0.000a

0.933

SE (D)

−3.98 ± 3.41

−4.25 ± 2.89

−4.97 ± 2.02

0.280

0.944

0.353

A1V (m/s)

0.15 ± 0.02

0.16 ± 0.03

0.15 ± 0.02

0.021a

0.213

0.841

A2V (m/s)

−0.38 ± 0.04

−0.352 ± 0.09

−0.34 ± 0.04

0.069

0.244

0.055

PD (mm)

4.90 ± 0.22

4.82 ± 0.23

4.82 ± 0.24

0.428

0.541

0.409

HCR (mm)

6.81 ± 0.60

5.36 ± 0.76

6.64 ± 0.52

0.000a

0.000a

0.550

HCDfA (mm)

1.10 ± 0.10

1.14 ± 0.12

1.07 ± 0.09

0.018a

0.430

0.508

SP-A1

107.05 ± 15.84

71.67 ± 17.34

99.49 ± 12.66

0.000a

0.000a

0.203

IR

8.78 ± 0.88

12.41 ± 2.43

9.38 ± 0.90

0.000a

0.000a

0.316

ARTh

412.88 ± 64.94

206.41 ± 80.57

363.70 ± 50.89

0.000a

0.000a

0.016a

DA ratio

4.37 ± 0.37

5.55 ± 0.85

4.47 ± 0.43

0.000a

0.000a

0.816

TBIb

0.17 ± 0.15

1.00

0.49 ± 0.28

–

0.000a

0.004a

CBIb

0.13 ± 0.18

0.99 ± 0.04

0.23 ± 0.30

–

0.000a

1.000

Flat K (D)b

42.52 ± 0.97

45.27 ± 2.47

43.20 ± 1.34

–

0.000a

0.019a

Steep K (D)

43.56 ± 1.29

48.67 ± 3.43

44.41 ± 1.43

0.000a

0.000a

0.015a

EPT (μm)

53.53 ± 2.00

48.17 ± 3.16

53.52 ± 2.26

0.000a

0.000a

0.936

BLT (μm)

17.96 ± 1.58

15.69 ± 1.32

16.12 ± 1.19

0.000a

0.000a

0.000a

STT (μm)

480.65 ± 32.01

414.10 ± 29.43

460.57 ± 33.89

0.000a

0.000a

0.074

  1. Normal = normal group; KC = keratoconus group; SKC = suspected keratoconus group; n = number of eyes; Cylinder = cylindrical power; SE = spherical equivalent; A1V = corneal apex velocity at first applanation; A2V = corneal apex velocity at second applanation; PD = peak distance; HCR = highest concavity radius of curvature; HCDfA = deflection amplitude at highest concavity; SP-A1 = stiffness parameter at first applanation; IR = integrated radius; ARTh = Ambrosio relational thickness to the horizontal profile; DA = deformation amplitude; TBI = tomographic and biomechanical index; CBI = Corvis biomechanical index; Flat K = flat keratometry; Steep K = steep keratometry; EPT = epithelial thickness; BLT = Bowman’s layer thickness; STT = stromal thickness; D = diopter; aP < 0.05; bKruskal-Wallis test