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Table 4 Multivariate regression analysis of associations with lens power stratified by age of 75 years and AL of 25 mm

From: The associations of lens power with age, axial length and type 2 diabetes mellitus in Chinese adults aged 50 and above

Variables

Age (years)

AL (mm)

50 ≤ Age < 75, N = 3180

Age ≥ 75, N = 590

AL < 25, N = 3350

AL ≥ 25, N = 420

Estimate, 95% CI

p value

Estimate, 95% CI

p value

Estimate, 95% CI

p value

Estimate, 95% CI

p value

Age

−0.103 (−0.114, −0.092)

< 0.001

−0.056 (−0.105, −0.008)

0.023

−0.080 (−0.088, −0.071)

< 0.001

−0.077 (−0.107, −0.046)

< 0.001

Sex

0.224 (0.061, 0.387)

0.007

0.027 (−0.497, 0.552)

0.918

0.124 (−0.036, 0.284)

0.127

0.312 (−0.207, 0.830)

0.238

Type 2 DM

0.591 (0.477, 0.705)

< 0.001

0.286 (−0.076, 0.647)

0.122

0.506 (0.395, 0.617)

< 0.001

0.260 (−0.114, 0.635)

0.172

AL

−0.722 (−0.778, −0.666)

< 0.001

−0.982 (−1.216, −0.748)

< 0.001

−1.487 (−1.585, −1.389)

< 0.001

−0.225 (−0.388, −0.062)

0.007

LT

1.132 (0.934, 1.331)

< 0.001

1.153 (0.592, 1.715)

< 0.001

1.133 (0.943, 1. 322)

< 0.001

1.205 (0.571, 1.839)

< 0.001

ACD

−0.623 (−0.843, −0.403)

< 0.001

0.017 (−0.681, −0.715)

0.962

0.094 (−0.132, 0.319)

0.415

−1.113 (−1.782, −0.444)

0.001

CP

−0.195 (−0.238, −0.152)

< 0.001

−0.272 (−0.408, −0.136)

< 0.001

−0.409 (−0.456, −0.362)

< 0.001

−1.133 (−0.260, −0.006)

0.040

Height

−0.023 (−0.033, −0.013)

< 0.001

−0.022 (−0.051, 0.008)

0.151

−0.019 (−0.028, −0.009)

< 0.001

−0.019 (−0.049, 0.011)

0.212

IOP

0.026 (0.007, 0.045)

0.008

−0.032 (−0.091, 0.027)

0.289

0.012 (−0.006, 0.030)

0.201

0.008 (−0.058, 0.074)

0.819

Advanced cataract

0.210 (0.012, 0.407)

0.037

0.535 (0.164, 0.907)

0.005

0.401 (0.232, 0.571)

< 0.001

0.505 (0.001, 1.009)

0.050

  1. Multivariate regression analysis was used to explore the relationship between lens power and Type 2 DM after adjusting for age, sex, AL, LT, ACD, CP, height, IOP, and advanced cataract in subgroups stratified by age of 75 years and AL of 25 mm. R2 for age < 75 years: 0.435; R2 for age ≥ 75 years: 0.244; R2 for AL < 25 mm: 0.408; R2 for AL ≥ 25 mm: 0.182
  2. ACD = anterior chamber depth; AL = axial length; CI = confidence intervals; CP = corneal power; D = diopter; DM = diabetic mellitus; IOP = intraocular pressure; LT = lens thickness; SD = standard deviation; SE = spherical equivalents