Fig. 2
From: The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy
Gene differentiation analysis. a Volcano plots of all detected mRNAs in the GO and Control groups. The red dots represent significantly upregulated genes (log2 fold change > 1 and adjusted P < 0.05); the blue dots represent significantly downregulated genes (log2 fold change <−1 and adjusted P < 0.05); the black dots under the red line indicate that no change of the in the expression levels of those genes were found, and there was no statistical differences of the gene expression levels for those above the red line. b Heatmap from the hierarchical clustering analysis showed the differential expressed mRNAs between the two groups. The color scale on the top illustrates the relative expression level of mRNAs across all samples: red denotes mRNA expression greater than the average value, and green denotes mRNA expression lesser than the average value